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BlockVid: Block Diffusion for High-Quality and Consistent Minute-Long Video Generation
BlockVid represents a major leap forward in long-video generation, tackling one of the hardest open problems in video generation, i.e, producing coherent, high-fidelity, minute-long clips without collapse, drift, or degradation over time. Developed by DAMO Academy, ZIP Lab, and Hupan Lab, BlockVid enhances the semi-autoregressive block diffusion paradigm with innovations that directly address KV-cache error… →
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Roasting oat-based paste modulates postprandial glucose and insulin sensitivity: Roles of acrylamide, texture, and starch fractions
Oat-based foods are widely recommended for dysphagia management and glycemic control, yet the impact of roasting conditions on their health benefits remains unclear. This study compared the postprandial glycemic and insulinemic responses to oat pastes prepared from low-temperature (90-110 °C) and conventional high-temperature (160 °C) roasted oat flours, using refined rice (R) as a reference,… →
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Efficacy and safety of PD-L1 blockade envafolimab as neoadjuvant treatment in mismatch repair-deficient, locally advanced colorectal cancer: An open-label, single-arm study
CONCLUSIONS: This preliminary study suggests that envafolimab is a promising effective and safe neoadjuvant option for locally advanced dMMR CRC; confirmation in larger cohorts is awaited. →
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Effects of finerenone on arterial stiffness and cardiorenal biomarkers in patients with type 2 diabetes and chronic kidney disease: a randomised placebo-controlled mechanistic trial (FIVE-STAR)
CONCLUSIONS: Finerenone did not affect changes in vascular stiffness but led to a significant and sustained reduction in albuminuria in patients with T2D and CKD. The clinical benefits of finerenone may result from lowering intraglomerular pressure rather than from its effect on vascular stiffness. →
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3 Tips for Ethical Decision-Making
In any organization, leaders are responsible for making decisions. Some decisions, like where to open a new location or whether to change prices, can largely be decided based on research, rational discussion, and clear lanes of decision-making authority. But other decisions boil down to value-based judgements, bringing out strong opinions and offering no easy answers.… →
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Lessons from Snowflake’s CRO
Hello and welcome to The GTMnow Newsletter by GTMnow – a weekly publication by VC firm, GTMfund. Build, scale and invest with the best minds in tech. This is Part III in our series on lessons from some of the top 1% leaders in B2B SaaS. In case you missed them: Part I: Canva’s CCO… →
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Cost-effectiveness of a single-layer high compression bandage versus Unna’s boot for venous leg ulcer treatment: the VENOS trial
CONCLUSION: In this study, SLHCB was cost-effective when compared with UB. These findings may prompt decision-makers to weigh the prospect of allocating an additional R$1.07 (I$0.42) for each percentage point reduction in VLU area or R$1739.13 (I$687.40) per QALY gained. This financial consideration holds significant implications for guiding resource allocation. →
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Efficacy of the Combination Therapy of Intense Pulsed Light and Microneedling With a Postbiotic Formulation for Melasma
CONCLUSION: The combination therapy of IPL and microneedling with a postbiotic formulation exhibits a multidimensional synergistic effect, presenting a promising new direction for melasma therapy. →
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The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial
CONCLUSION: A facial mask based on Bentonite and A. sulphurea extract effectively reduces acne severity and enhances patient satisfaction. These findings suggest its potential as a natural alternative or adjunct to conventional acne treatments. →
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Cost-effectiveness of a self-management maintenance programme following pulmonary rehabilitation: a UK randomised controlled trial for patients with chronic obstructive pulmonary disease
INTRODUCTION: Pulmonary rehabilitation (PR) is an effective intervention for patients with chronic obstructive pulmonary disease (COPD) but impact typically only lasts 6-12 months. This paper presents results of an economic evaluation of a PR maintenance programme (Self-management Programme of Activity, Coping and Education (SPACE)) undertaken within a prospective assessor-blind randomised controlled trial. →
