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  • Early response to vunakizumab and its baseline predictors in patients with moderate-to-severe plaque psoriasis: a post hoc analysis of a phase-III trial

    25 сентября, 2025

    CONCLUSION: Early response rate to vunakizumab was 54.0% in patients with moderate-to-severe plaque psoriasis, where female gender and naïve status to local therapy predicted early response. →

    Clinical Trials
  • Effect of Motivational Interviewing on Exclusive Breastfeeding in Working Mothers: A Randomized Controlled Trial

    25 сентября, 2025

    CONCLUSIONS: The present study revealed that single-session MI telephone-based intervention helped boost maternal motivation for EBF, especially for those with inadequate BSE. Public health interventions that help nurture breastfeeding friendly culture in the workplace and community should be coupled with individualized interventions to dampen early cessation of breastfeeding. →

    Clinical Trials
  • Ultrasound-guided nerve block anesthesia improves perioperative pain in patients undergoing free flap reconstruction for head-and-neck tumor: a randomized, controlled trial

    25 сентября, 2025

    CONCLUSION: Ultrasound-guided iliac fascia combined with trigeminus block anesthesia is an effective method for pain management in patients who underwent head-and-neck tumor surgery in conjunction with the simultaneous repair using the vascularized anterolateral femoral free flap. →

    Clinical Trials
  • Meta FAIR Released Code World Model (CWM): A 32-Billion-Parameter Open-Weights LLM, to Advance Research on Code Generation with World Models

    25 сентября, 2025

    Meta FAIR Released Code World Model (CWM): A 32-Billion-Parameter Open-Weights LLM to Advance Research on Code Generation with World Models Understanding the Target Audience The target audience for the Meta FAIR Code World Model (CWM) primarily includes: Researchers and Academics: Individuals focused on advancing AI and machine learning, particularly in code generation and software engineering.… →

    AI News
  • Exploring the feedback effects of incentive methods on HIV rapid self-testing among men who have sex with men in Chongqing, China

    25 сентября, 2025

    CONCLUSION: Our results show no significant differences in feedback rates across groups at follow-up time points. Significant differences in feedback rate trends among the three groups were observed, with the extra lottery incentive providing more sustained motivation for feedback. And privacy concerns are crucial for expanding HIVST among MSM via social apps. →

    Clinical Trials
  • Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity

    25 сентября, 2025

    EGFRex20 insertions (EGFRex20ins) can be classified as near- and far-loop based on the insertion location, however, the impact of location on responses to various EGFR tyrosine kinase inhibitors (TKIs) is poorly understood. In vitro studies show that afatinib, poziotinib, and zipalertinib more potently inhibited near-loop than far-loop insertions, whereas mobocertinib has similar IC(50) in both… →

    Clinical Trials
  • Percutaneous Coronary Intervention in Multivessel Disease and Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy

    25 сентября, 2025

    CONCLUSIONS: Immediate multivessel PCI was associated with 60% lower odds of all-cause mortality compared with culprit-only PCI. →

    Clinical Trials
  • Efficacy of In-office Bleaching Gel One Week After Mixing: A Randomized Clinical Trial

    25 сентября, 2025

    CONCLUSION: In-office dental bleaching with Opalescence Boost PF 40% remained effective, without differences in risk and intensity of TS and GI, even 1 week after mixing. →

    Clinical Trials
  • How to Build an End-to-End Data Science Workflow with Machine Learning, Interpretability, and Gemini AI Assistance?

    25 сентября, 2025

    «`html Understanding the Target Audience The target audience for this tutorial includes data scientists, machine learning engineers, and business analysts who are interested in building robust and interpretable data science workflows. These individuals typically work in technology-driven industries where data-driven decision-making is essential. Pain Points Difficulty in understanding and interpreting machine learning models Need for… →

    AI News
  • How LLMs Work: Top 10 Executive-Level Questions

    25 сентября, 2025

    Carolyn Geason-Beissel/MIT SMR | Getty Images In my work at MIT Sloan School of Management, I have taught the basics of how large language models (LLMs) work to many executives during the past two years. Some people posit that business leaders neither want to nor need to know how LLMs and the generative AI tools… →

    Management
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