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Multicenter open prospective randomized study on the efficacy and safety of Canephron N in preventing recurrences of uncomplicated lower urinary tract infection in women
CONCLUSION: Evidence has been obtained supporting the therapeutic efficiency of Canephron N in the combination treatment and prevention of recurrent UTIs. A positive trend was observed toward improved treatment outcomes and reduced recurrence rates in real clinical practice among patients with uncomplicated cystitis receiving the herbal product in combination with antibiotic therapy. →
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Adoption of plasma D-dimer testing, color Doppler ultrasound, and enoxaparin sodium in predicting and preventing lower extremity deep vein thrombosis in high-risk parturients undergoing cesarean section
This study aims to explore the clinical value of plasma D-dimer (D-D) testing, color Doppler ultrasound, and enoxaparin sodium in predicting and preventing lower extremity deep vein thrombosis (DVT) in high-risk parturients undergoing cesarean section. Eighty-six high-risk parturients were randomly rolled into an observation (Obs) group and a control (Ctrl) group (86 cases each). Ctrl… →
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Cost-Utility Analysis and Value-Based Pricing of Digital Therapeutics for Pulmonary Rehabilitation in Chronic Respiratory Disease: Economic Evaluation Based on a Randomized Controlled Trial
CONCLUSIONS: DTx for pulmonary rehabilitation demonstrated the cost-effectiveness compared with standard treatment. These findings support its potential for improving outcomes in patients with chronic respiratory disease and provide a pricing framework to facilitate its integration into health care systems. →
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Hormonal mechanisms of women’s risk in the face of traumatic stress
Women are underrepresented in biomedical research, limiting understanding of their disproportionate rates of stress-related disorders. Although men experience more trauma, women are twice as likely to develop posttraumatic stress disorder (PTSD). We tested whether ovarian hormones contribute to this disparity via their influence on threat-related brain activity. In a randomized, double-blind crossover study of 110… →
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Beat Burnout: 10 Essential MIT SMR Reads
Many employees feel stretched thin right now — facing excessive workloads, unclear expectations, and a lack of meaningful connection at work. This kind of burnout quietly erodes people’s motivation and sense of well-being. At the other end of the spectrum, the most fulfilled workers say that they are challenged and inspired in their roles and… →
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Digital Cognitive Behavioral Treatment for Generalized Anxiety Disorder: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, DCBT provided significant and sustained benefits to adults with GAD. Given the limitations in access to empirically supported CBT, an efficacious DCBT program has clear potential for public health benefit. →
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VC 2: How Cassie Young Picks Winners Before They Even Leave Their Jobs
Brought to you by: AngelList How did we build the GTMfund back office? Easy! We leveraged AngelList’s Rolling Fund product for Fund I, which was the perfect vehicle to scale up GTMfund in its first iteration. This structure allowed us to build our network, and add revenue leaders while we raised and deployed capital simultaneously,… →
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Effectiveness and cost-effectiveness of a multimodal, physiotherapist-led, vocational intervention for people with rheumatoid arthritis or axial spondyloarthritis and a reduced work ability: a randomized, controlled trial
To evaluate the (cost-)effectiveness of a physiotherapist-led, multimodal vocational intervention compared to usual care in adults with rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA) experiencing reduced work ability. (Self-)employed people with RA or axSpA and reduced work ability were randomized to a 12-month vocational intervention or usual care. Assessments were conducted at baseline, 3, 6,… →
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Omni-Attribute: Open-Vocabulary Attribute Encoder for Visual Concept Personalization
Omni-Attribute introduces a new paradigm for fine-grained visual concept personalization, solving a long-standing problem in image generation: how to transfer only the desired attribute (identity, hairstyle, lighting, style, etc.) without leaking irrelevant visual details. Developed by researchers from Snap Inc., UC Merced, and CMU, this work proposes the first open-vocabulary image attribute encoder explicitly designed… →