Advances in Precision Psychiatry: Integrating AI and Machine Learning: Precision psychiatry, merging psychiatry, precision medicine, and pharmacogenomics, aims to deliver personalized treatments for psychiatric disorders. AI and machine learning, particularly deep learning, have enabled the discovery of numerous biomarkers and genetic loci associated with these conditions. This review highlights integrating neuroimaging and multi-omics data with…
Large-scale generative models like GPT-4, DALL-E, and Stable Diffusion have transformed artificial intelligence, demonstrating remarkable capabilities in generating text, images, and other media. However, as these models become more prevalent, a critical challenge emerges the consequences of training generative models on datasets containing their outputs. This issue, known as model collapse, poses a significant threat…
A critical aspect of AI research involves fine-tuning large language models (LLMs) to align their outputs with human preferences. This fine-tuning ensures that AI systems generate useful, relevant, and aligned responses with user expectations. The current paradigm in AI emphasizes learning from human preference data to refine these models, addressing the complexity of manually specifying…
The notorious middle-of-the-night unactionable alert is well known to those on-call, adding to the stress that on-call engineers endure. It is still difficult to tell when something has gone wrong, how it has affected the user, and how to correct it fast, even with contemporary technologies. Examining an alert alone makes it difficult to grasp…
In the digital age, personalized experiences have become essential. Whether in customer support, healthcare diagnostics, or content recommendations, people expect interactions with technology to be tailored to their specific needs and preferences. However, creating a truly personalized experience can be challenging. Traditional AI systems cannot often remember and adapt based on past interactions, resulting in…
The Sparse Autoencoder (SAE) is a type of neural network designed to efficiently learn sparse representations of data. The Sparse Autoencoder (SAE) neural network efficiently learns sparse data representations. Sparse Autoencoders (SAEs) enforce sparsity to capture only the most important data characteristics for fast feature learning. Sparsity helps reduce dimensionality, simplifying complex datasets while keeping…
Recent advances in immune sequencing and experimental methods generate extensive T cell receptor (TCR) repertoire data, enabling models to predict TCR binding specificity. T cells play a role in the adaptive immune system, orchestrating targeted immune responses through TCRs that recognize non-self antigens from pathogens or diseased cells. TCR diversity, essential for recognizing diverse antigens,…