Clinical Trials
Category Added in a WPeMatico Campaign
-
Osa in women: When does cpap increase blood pressure?
CONCLUSION: Greater age, the presence of depression and higher baseline AHI and SBP were independently associated with a clinical significant increase in BP after CPAP, regardless of their adherence. These changes in BP appeared mainly during the first month of treatment.
-
How Does Mobile Technology Shape the Perceptions of People with Type 2 Diabetes?
We conducted a randomised clinical trial involving 43 patients diagnosed with type 2 diabetes. For four weeks, participants used the forDiabetes: diabetes self-management mobile app. Using a questionnaire to assess perceptions of the disease, we observed how the use of mobile technology affects perceptions of the disease. We found that participants in the mobile app…
-
Efficacy of Non-Ablative Fractional Laser Combined With Tranexamic Acid in Melasma Treatment: A Randomized Split-Face Trial
CONCLUSIONS: The combination of NAFL and topical TXA provides significant short-term clinical benefits in treating melasma, likely by enhancing TXA penetration into target tissues and improving pigmentary clearance. However, its efficacy diminishes over time due to the inevitable recurrence of melasma, necessitating further investigation into long-term maintenance strategies.
-
Barriers to Digital Mental Health Services Among College Students
This qualitative study explores barriers to digital mental health Intervention (DMHI) use among college students. Data are from a randomized trial of eBridge, which used motivational interviewing to connect students with mental health concerns to professional care. Thematic analysis of participant feedback on their experience with the DMHI platform revealed nine key obstacles to adoption:…
-
Impact of an Evidence-Based Large Language Model (LLM) Diagnostic Decision Support System: A Randomised Controlled Trial
Generative artificial intelligence (AI) influences clinical decision-making in healthcare by analyzing medical data and proposing personalized treatment options based on patient records. However, generative AI limited due to its inability to provide accurate evidence. Therefore, this study aims that the influence of AI-generated diagnostic suggestions on emergency healthcare providers’ diagnostic patterns and decision-making, and evaluates…
-
Petal-x Visualization for Lifestyle Change in Patients at Risk of Cardiovascular Diseases: An Evaluation
Cardiovascular diseases (CVDs) are the leading global cause of death and addressing unhealthy lifestyles is essential for reducing CVD risk. Visual explanations, such as the Petal-X dashboard, can support personalized care by improving patients’ understanding of health risks and motivating lifestyle changes. This study evaluated whether the Petal-X dashboard, utilizing the SCORE2 model for 10-year…
-
The effect of hope-based counseling on perceived stress and the quality of life in pregnant women experiencing nausea and vomiting: a randomized control trial
CONCLUSION: Counseling based on hope therapy was effective in reducing perceived stress and improving the quality of life for pregnant women experiencing nausea and vomiting. Implementing this approach could be a valuable strategy for health policymakers to enhance the quality of life for pregnant women, particularly those dealing with pregnancy-related nausea and vomiting.
-
Effects of combined supervised and telerehabilitation exercise programs on pain and disability in dentists with chronic neck pain: a randomized controlled trial
CONCLUSIONS: The results showed that combined exercises applied under supervision were more effective than telerehabilitation or home exercises in dentists with CNP, and telerehabilitation was more effective than home program. Although the telerehabilitation method is not as effective as supervised exercise training, it can be an alternative method to reduce pain and disability for dentists…
-
Open-Label Study: Over-the-Counter Oat Flour/Oat Oil/ Oat Extract-containing Lotion With Avenanthramides for Sensitive Skin and Psoriasis
CONCLUSIONS: This study provides evidence supporting the efficacy and tolerability of a topical, over-the-counter lotion containing oat flour, oat oil and oat extract with avenanthramides as the sole intervention for managing the symptoms of sensitive skin and mild to moderate psoriasis.
-
Safety and Tolerability of Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel for Truncal Acne
CONCLUSIONS: In this pooled analysis, fixed-dose CAB gel was well tolerated over 12 weeks in participants treating their truncal acne. The lack of safety signals combined with the favorable safety/tolerability profile of CAB shows that it is a safe treatment option for truncal and facial acne.