Clinical Trials
Category Added in a WPeMatico Campaign
-
Effects of an Aquatic Exercise Protocol on Blood Pressure, Respiratory Function, and Functional Capacity in Individuals with Type 2 Diabetes: A Randomized Controlled Trial
CONCLUSION: It is concluded that five-week aquatic training reduced systolic and diastolic blood pressure and functional capacity over time. However, when compared to the groups, no changes were observed in the analyzed parameters.
-
Effect of mat Pilates on postural control in breast cancer survivors receiving endocrine therapy: a randomized controlled clinical trial
CONCLUSIONS: These findings suggest that Mat Pilates may be a clinically effective, low-cost, and adaptable strategy for improving postural control and potentially reducing fall risk in BCS.
-
Comparison of two different pilates exercise methods in individuals with Ankylosing Spondylitis: A randomized controlled study
OBJECTIVE: The study aimed to compare the effectiveness of two different Pilates exercise methods (mat Pilates vs reformer Pilates) in individuals with Ankylosing Spondylitis (AS).
-
Differences Among Veterans With Chronic Overlapping Pain Conditions and Other Chronic Pain: Baseline Results From the LAMP Pain Management Trial
CONCLUSIONS: COPCs were common among a sample of veterans in a pragmatic clinical trial. Several baseline differences emerged indicating veterans with COPCs experience greater mental health concerns and endorse distinct pain characteristics and pain mediators. Future research is needed to further characterise this recently defined and under-represented group.
-
Effect of Selenomethionine— Enriched Yeast on Hypothyroidism Patients
Selenium (Se) is a trace mineral that plays a critical role in public health. It is a vital component of numerous enzymes and proteins called selenoproteins, thus affecting a wide range of biological activities. Hashimoto’s disease is the most common cause of hypothyroidism. In addition to being a critical micronutrient for thyroid health, selenium has…
-
Comparative Effectiveness of Gabapentin and Pregabalin Combination Therapy in Postherpetic Neuralgia: A Single-Masked Randomised Controlled Trial
CONCLUSION: The combination therapy with gabapentin and low-dose pregabalin could help reduce pain and inflammatory factors.
-
Presleep vs. Daytime Consumption of Casein-Enriched Milk: Effects on Muscle Function and Metabolic Health After Sleeve Gastrectomy
Background/Objectives: This randomized controlled trial aimed to evaluate the effects of casein-enriched milk (CEM) consumption and its timing (presleep vs. during the day) in the early postoperative period on body composition, muscle strength, physical function, and biochemical parameters in individuals undergoing laparoscopic sleeve gastrectomy (SG). Methods: Forty-five adults (60% female, 40% male; mean age 35.1…
-
The Efficacy and Safety of Transcranial Photobiomodulation for Mild Cognitive Impairment Due to Alzheimer’s Disease: A Randomized, Double-Blind, Sham-Controlled Study
Background: Transcranial photobiomodulation (tPBM) is a promising noninvasive neuromodulation modality with potential therapeutic benefits for neurodegenerative diseases. Infrared light delivered by a tPBM device penetrates the cortex, stimulating neuronal activity by increasing mitochondrial adenosine triphosphate production and enhancing regional cerebral blood flow. Objective: This study investigated the efficacy and safety of a self-administered, at-home, wearable…
-
Evaluating the training outcomes of single-console and dual-console da Vinci surgical systems: a randomized controlled trial
This study evaluated the dual-console collaborative training mode for robotic Surgical skills using the da Vinci Surgical System. In a randomized controlled trial, 24 PGY-1 residents were assigned to either dual-console training or single-console training. The SimNow^(®) simulator assessed operative efficiency, recording errors, such as Misapplied Energy, Instrument-Instrument Collisions, and Instruments Out of View. Operative…
-
Phase 2 trial of personal dendritic cell vaccines in newly diagnosed glioblastoma: 3-year follow-up and correlations with survival
Survival of glioblastoma (GBM) patients is unsatisfactory. Adding patient-specific vaccines to standard therapy may improve outcomes. Autologous dendritic cells (DC) loaded with autologous tumor antigens (ATA) from short-term cell lines established from autologous tumor are a promising therapeutic vaccine strategy. DC-ATA vaccines were tested in a single-arm phase 2 trial in newly diagnosed GBM patients.…