Clinical Trials
Category Added in a WPeMatico Campaign
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Wearable Augmented Reality for Nystagmus Examination in Patients With Vertigo: Randomized Crossover Usability Study
We demonstrate the feasibility of a wearable, augmented reality-based nystagmus examination system, showing its preliminary diagnostic agreement with conventional video-oculography and its potential for portable vestibular assessment in patients with vertigo.
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Comparing botulinum toxin and biofeedback therapies for awake bruxism: a randomized clinical trial
CONCLUSION: Even though neither intervention improved pain nor psychosocial outcomes, BIO significantly reduced AB behaviors, indicating that BIO may be preferable for controlling AB behaviors in TMD patients.
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Uptake of community-based integrated HIV and sexual and reproductive health services for young people in Zimbabwe: the CHIEDZA study
CONCLUSIONS: An integrated HIV and SRH programme had high attendance and service uptake, with most clients accessing multiple service components per visit, including HIV testing. Provision of integrated HIV and SRH services may increase service engagement and uptake by young people and facilitate programme efficiency.
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Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta
CONCLUSIONS: The TOPaZ population represents a unique cohort with which to study the genetic epidemiology and outcome of OI in relation to bone density and biochemical markers of bone turnover. When the trial reports, it will also provide new insights into the effect of an anabolic therapy, followed by antiresorptive treatment in the management of…
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Effectiveness of strenghtning oropharyngeal myofunctional therapy combined with cervical spine exercises in mild to moderate obstructive sleep apnoea
CONCLUSION: The comprehensive 20-week OMT programme and cervical spine exercises showed no effectiveness in improving respiratory parameters, daytime sleepiness or quality of life in patients with mild to moderate OSA compared to hygiene- and diet-related measures alone. The null results observed in this study suggest relevant clinical implications, such as the limited efficacy of low-frequency…
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Opening the black box: defining true-negative outcomes in esophageal cancer screening — a population-based study
CONCLUSIONS: Individuals with normal Lugol staining should be considered the genuinely screening-negative population for esophageal cancer. A 10-year screening interval is recommended for normal-stained individuals, while 2-3 years are necessary for ND-LULs.
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A study on Mahjong intervention to improve cognitive impairment in patients with schizophrenia: a pilot, single-blind, randomized, controlled trial
CONCLUSION: While this exploratory study suggests that Mahjong intervention may benefit certain cognitive functions and quality of life in patients with schizophrenia, these findings should be interpreted with caution. Further research with larger, more diverse samples and longer intervention is necessary to confirm and extend these findings.
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Motivational Framing Strategies in Health Care Information Security Training: Randomized Controlled Trial
CONCLUSIONS: This study underscores the importance of aligning SETA programs with the professional values of target groups, in addition to adapting these programs to specific contexts of professional action. In the investigated hospital setting, a motivational framing that resonates with health care professionals’ sense of responsibility for patient safety has proven to be effective in…
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Low-Molecular-Weight Heparin Plus Insulin in Hypertriglyceridemic Acute Pancreatitis: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, the combination of LMWH and insulin failed to demonstrate superior efficacy vs insulin alone in patients with hypertriglyceridemic acute pancreatitis. LMWH might not be necessary for early lipid-lowering in hypertriglyceridemic acute pancreatitis.
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Impact of anchoring bias in medical diagnostic decision-making: an experimental study
CONCLUSIONS: The findings highlight the importance of addressing cognitive biases -particularly anchoring bias- in medical training to improve diagnostic accuracy and reduce clinical errors.