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BACKGROUND: Diagnostic error is a frequent and clinically relevant health-care problem. Whether computerised diagnostic decision support systems (CDDSSs) improve diagnoses is controversial, and prospective randomised trials investigating their effectiveness in routine clinical practice are scarce. We hypothesised that diagnoses made with a CDDSS in the emergency department setting would be superior to unsupported diagnoses.
CONCLUSION: This is the first report to demonstrate a link between increased IL-18F levels and pain scales in MLa. IL-18F levels decreased significantly after operation and correlated with IL-18, IL-18BP, and 4-HNE blood levels, and inversely correlated with BPI pain scores. These results support the applicability of acute phase response biomarkers in understanding pain in…
BACKGROUND: Children with autism spectrum disorder (ASD) are known to experience difficulties in coordinating fine- and gross-motor movement. Previous interventional studies have reported significant effect of exercise-based intervention programs on improving motor skills and alleviating symptoms in ASD; however, researchers are yet to know why some participants experienced less improvement than others. One plausible explanation…
CONCLUSIONS: Short-term reduction of FFA concentration does not improve insulin-stimulated vasodilation in patients with metabolic syndrome.
CONCLUSIONS: This is one of the first interventions to address FCR in FC. While acceptability of FC-FORT was good, important feasibility issues need to be addressed before moving forward with a larger randomized control trial.
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, AQCS assistance during routine colonoscopy increased adenoma detection rates and several related polyp parameters compared with standard colonoscopy in the lower- and medium-level detectors in academic and nonacademic settings. Routine use of AQCS to assist in colorectal adenoma detection and quality improvement should be considered.
CONCLUSION: The Moyo FHR monitor has demonstrated efficacy in detecting abnormal FHRs when compared with the Pinard fetoscope.
BACKGROUND: People with malignancy of undefined primary origin (MUO) have a poor prognosis and may undergo a protracted diagnostic workup causing patient distress and high cancer related costs. Not having a primary diagnosis limits timely site-specific treatment and access to precision medicine. There is a need to improve the diagnostic process, and healthcare delivery and…
CONCLUSIONS: In individuals with intermediate coronary stenosis, elevated angio-IMR is linked to an adverse prognosis. Using angio-IMR significantly enhanced the capability to reclassify patients and accurately estimate the risk for the POCO.
CONCLUSION: According to best trial practices, we report our statistical analysis plan and data management plan prior to locking the database and initiating the analyses. We anticipate that this practice will prevent analysis bias and improve the utility of the study’s reported results.