Clinical Trials
Category Added in a WPeMatico Campaign
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Outcomes After CABG Compared With FFR-Guided PCI in Patients Presenting With Acute Coronary Syndrome
CONCLUSIONS: The risk of death, MI, or stroke at 3 years was similar after CABG compared with FFR-guided PCI in patients presenting with NSTE-ACS, but reduced by CABG in patients presenting with CCS. (Fractional flow reserve versus Angiography for Multivessel Evaluation [FAME 3]; NCT02100722).
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Early psychosis service user views on digital remote monitoring: a qualitative study
CONCLUSIONS: This study shed light on early psychosis service users’ experiences with using the ClinTouch digital remote monitoring app. ClinTouch was viewed as acceptable for monitoring symptoms, safe and easy to use, showed potential of integration with clinical care, and facilitated increased awareness and understanding of symptoms. Improvements including personalised question items and interactive features…
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PRERISK Study: A Randomized Controlled Trial Evaluating a sFlt-1/PlGF-Based Calculator for Preeclampsia Hospitalization
CONCLUSIONS: Routine screening with the PRERISK score and a 5% cutoff in patients with suspected or confirmed preeclampsia does not decrease hospitalization and is therefore not recommended.
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Experience with the use of undenatured type II collagen in patients with stage III knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial
CONCLUSION: Artneo showed high efficacy and safety in the general population of patients, including those with stage III knee OA.
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Predicting Postoperative Circulatory Complications in Older Patients: A Machine Learning Approach
CONCLUSION: We have developed and validated an algorithm for predicting PCCs in elderly patients by identifying key risk factors.
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Non-Invasive Auricular Acupoint Stimulation Improves Slow-Transit Constipation: Evidence From a Randomized Controlled Trial
BACKGROUND Slow-transit constipation lacks optimal therapies due to the adverse effects and limited efficacy of current treatments. Auricular acupoint stimulation offers a potential adjunctive approach through neuromodulation, yet its clinical efficacy and mechanistic role in slow-transit constipation remain unestablished. MATERIAL AND METHODS Sixty patients diagnosed with slow-transit constipation, ranging in age from 40 to 75…
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High-intensity interval training improves insulin sensitivity in individuals with prediabetes
CONCLUSIONS: Twelve weeks of low-volume HIIT training can improve glucose control and induces adaptations in skeletal muscle important for metabolic health in individuals with prediabetes.
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Four cycles of docetaxel plus cisplatin as neoadjuvant chemotherapy followed by concurrent chemoradiotherapy in stage N2-3 nasopharyngeal carcinoma: phase 3 multicentre randomised controlled trial
CONCLUSIONS: Four cycles of docetaxel plus cisplatin neoadjuvant chemotherapy with concurrent chemoradiotherapy can effectively reduce distant metastasis and improve survival for patients with stage N2-3 nasopharyngeal carcinoma with manageable toxicities.
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Mood reactivity to daily social conflict in hostile adults: An experimental intervention
CONCLUSIONS: Citalopram reduces hostile mood responses to social conflict during daily life in dispositionally hostile adults. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
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The efficacy of high-intensity laser and short-wave diathermy both combined with exercises in patients with knee osteoarthritis: a randomized comparative study
The present study aimed to investigate the effects of high-intensity laser therapy and short-wave diathermy, both with exercise, on pain, physical function, and quality of life in patients with knee osteoarthritis and compare the efficacy of these modalities. This head-to-head randomized study included sixty patients diagnosed with primary knee osteoarthritis (OA) according to the American…