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INTRODUCTION: Postoperative delirium occurs in up to 40% of older surgical patients and has been associated with prolonged hospital stays, long-term cognitive impairment and increased 1-year postoperative mortality. Postoperative sleep disturbances may increase the risk of delirium, but studies investigating pharmacotherapies to improve postoperative sleep to prevent delirium remain limited. Suvorexant is a selective antagonist…
BACKGROUND: Previous studies have identified inequities in the diagnostic and therapeutic procedures used with community-dwelling people living with dementia (PlwDs) or people living with mild cognitive impairment (PlwMCIs) depending on the urban vs. rural location of their residence. Whether those differences in health care and health services utilization still exist for people residing in shared-housing…
CONCLUSION: Acute group fitness classes induce age-dependent alterations in blood pressure, but not in arterial stiffness or cardiovagal modulation. While the overall cardiovascular effects were generally consistent, differences in autonomic recovery were observed between exercise modes, with prolonged effects seen after indoor cycling. This suggests that exercise prescription should consider both age and exercise modality,…
No abstract
INTRODUCTION: Older patients with acute myeloid leukemia (AML) respond poorly to standard induction therapy. DNA methyltransferases (DNMTs) and histone-deacetylases (HDACs) are key regulators of gene expression in cells and have been investigated as important therapeutic targets. However, their effects remains unclear as induction therapy for AML.
INTRODUCTION: Primary headaches pose a significant burden on children and adolescents, highlighting the need for effective non-pharmacological interventions. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive modality that has demonstrated efficacy in adult populations with primary headaches and has shown safety in adolescents with mental health disorders. However, its effectiveness in managing acute headache…
CONCLUSION: Among patients who had lumbar puncture, our study shows the noninferiority of the absence of specific advice on water intake after a lumbar puncture, compared with advice to increase oral fluid to prevent a post-dural puncture headache.
CONCLUSION: In a randomized controlled pilot study, HRV biofeedback led to improved autonomic cardiac function and alleviated symptoms of depression in patients with functional dizziness, most likely mediated by a predominantly parasympathetic effect.
CONCLUSIONS: Intensive therapy based on a high cytarabine dose and continuously administered EDOCH achieved a high MRD-negative rate and provides an optional induction choice for young patients with MCL with high-risk factors.
CONCLUSIONS: Based on this multicentre study about ENI, the incidence of interruptions in enteral nutrition was 18.6%, with diagnostic and therapeutic procedures being the leading causes. The occurrence of interruptions in the delivery of enteral nutrition leads to a reduction in the nutritional intake of critically ill patients.