Clinical Trials
Category Added in a WPeMatico Campaign
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Defining the Profile of People With Emotional Disorders That Drop Out or Do Not Respond to Treatment After Receiving the Unified Protocol in Group Format
Dropout, defined as the unilateral discontinuation of treatment before achieving goals or completing a set number of sessions, affects a large number of individuals. Additionally, many individuals do not experience an improvement of symptoms after treatment. This study has explored the profile of individuals who drop out or do not respond favourably to the Unified…
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Statins to reduce renal sinus fat among breast cancer patients undergoing anthracycline-based chemotherapy: A substudy of PREVENT-WF-98213
OBJECTIVE: To test if statin administration attenuated renal sinus fat (RSF) accumulation and if RSF was associated with renal function in women with breast cancer (BC) receiving anthracycline-based chemotherapy.
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Effects of an Aquatic Exercise Protocol on Blood Pressure, Respiratory Function, and Functional Capacity in Individuals with Type 2 Diabetes: A Randomized Controlled Trial
CONCLUSION: It is concluded that five-week aquatic training reduced systolic and diastolic blood pressure and functional capacity over time. However, when compared to the groups, no changes were observed in the analyzed parameters.
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Effect of mat Pilates on postural control in breast cancer survivors receiving endocrine therapy: a randomized controlled clinical trial
CONCLUSIONS: These findings suggest that Mat Pilates may be a clinically effective, low-cost, and adaptable strategy for improving postural control and potentially reducing fall risk in BCS.
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Comparison of two different pilates exercise methods in individuals with Ankylosing Spondylitis: A randomized controlled study
OBJECTIVE: The study aimed to compare the effectiveness of two different Pilates exercise methods (mat Pilates vs reformer Pilates) in individuals with Ankylosing Spondylitis (AS).
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Differences Among Veterans With Chronic Overlapping Pain Conditions and Other Chronic Pain: Baseline Results From the LAMP Pain Management Trial
CONCLUSIONS: COPCs were common among a sample of veterans in a pragmatic clinical trial. Several baseline differences emerged indicating veterans with COPCs experience greater mental health concerns and endorse distinct pain characteristics and pain mediators. Future research is needed to further characterise this recently defined and under-represented group.
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Effect of Selenomethionine— Enriched Yeast on Hypothyroidism Patients
Selenium (Se) is a trace mineral that plays a critical role in public health. It is a vital component of numerous enzymes and proteins called selenoproteins, thus affecting a wide range of biological activities. Hashimoto’s disease is the most common cause of hypothyroidism. In addition to being a critical micronutrient for thyroid health, selenium has…
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Comparative Effectiveness of Gabapentin and Pregabalin Combination Therapy in Postherpetic Neuralgia: A Single-Masked Randomised Controlled Trial
CONCLUSION: The combination therapy with gabapentin and low-dose pregabalin could help reduce pain and inflammatory factors.
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Presleep vs. Daytime Consumption of Casein-Enriched Milk: Effects on Muscle Function and Metabolic Health After Sleeve Gastrectomy
Background/Objectives: This randomized controlled trial aimed to evaluate the effects of casein-enriched milk (CEM) consumption and its timing (presleep vs. during the day) in the early postoperative period on body composition, muscle strength, physical function, and biochemical parameters in individuals undergoing laparoscopic sleeve gastrectomy (SG). Methods: Forty-five adults (60% female, 40% male; mean age 35.1…
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The Efficacy and Safety of Transcranial Photobiomodulation for Mild Cognitive Impairment Due to Alzheimer’s Disease: A Randomized, Double-Blind, Sham-Controlled Study
Background: Transcranial photobiomodulation (tPBM) is a promising noninvasive neuromodulation modality with potential therapeutic benefits for neurodegenerative diseases. Infrared light delivered by a tPBM device penetrates the cortex, stimulating neuronal activity by increasing mitochondrial adenosine triphosphate production and enhancing regional cerebral blood flow. Objective: This study investigated the efficacy and safety of a self-administered, at-home, wearable…