Clinical Trials
Category Added in a WPeMatico Campaign
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A Randomized Clinical Trial Comparing the Effectiveness of Aerobic Training and Circuit Training on Balance in Ataxic Patients
BACKGROUND: The term ataxia refers to the inability to coordinate movement. It essentially happens when the cerebellum or any of its connections are damaged. A brain tumor, multiple sclerosis, stroke, cerebral palsy, certain drugs, and genetic illnesses are the few examples of the ailments that can result in ataxia. Although aerobic exercise helps ataxic people…
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Detrended Fluctuation Analysis of Gait Cycles: A Study of Neuromuscular and Ground Force Dynamics
Gait analysis provides crucial insights into neuromuscular coordination and postural control, especially in ageing populations and rehabilitation contexts. This study investigates the complexity of muscle activation and ground reaction force patterns during gait by applying detrended fluctuation analysis (DFA) to electromyography (EMG) and force-sensitive resistor (FSR) signals. Data from a two-arm randomised clinical trial (RCT)…
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The clinical performance of monoshade resin composite as posterior restoration: a randomized controlled clinical trial
The aim of this study was to assess the clinical performance of a monoshade universal resin composite as posterior restoration. Twenty adult patients having at least two carious lesions related to posterior teeth were selected. Each patient was provided with a monoshade resin composite (Omnichroma) and polyshade nanohybrid resin composite (Tetric^(®) N-Ceram) for class I…
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Prevention and treatment of social anxiety disorder in adolescents: mixed method randomised controlled trial of the guided online intervention SOPHIE
Social anxiety symptoms are highly prevalent in adolescents and negatively impact their social and academic functioning, highlighting the need for effective low-threshold interventions. This randomised controlled trial evaluated the guided online intervention SOPHIE for adolescents (N = 133; 11-17 years) with social anxiety disorder (SAD; treatment) or subclinical social anxiety (indicated prevention) compared to care-as-usual…
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Pattern Recognition Control of a 2 Degree-of-Freedom Prosthetic Device
For individuals with transradial limb loss or difference, myoelectric prostheses providing advanced functionality are often controlled through two control strategies: Amplitude and Threshold Control (ATC) and Pattern Recognition (PR). While ATC, a conventional method which is sometimes called direct control, is commonly used, it can be less intuitive for multi-degree-of-freedom tasks. PR, leveraging machine learning…
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Laser treatment for temporomandibular disorder: a randomized controlled clinical trial
This study aimed to assess the impact of photobiomodulation therapy (PBMT) using low-level laser therapy, an occlusal splint (OS), and their combined application (OSL) on symptoms of muscular temporomandibular disorder (TMD) through a randomized clinical trial. Participants diagnosed with muscular TMD following the Diagnostic Criteria for TMD guidelines were allocated to three groups: OS, L,…
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Effect of 0.8% Hyaluronic Acid-Based Gel on Clinical and Biomolecular parameters in the surgical periodontal treatment of Stage III periodontitis patients: a randomized, split-mouth clinical trial
CONCLUSION: The local application of 0.8% HA gel with OFD provides to beneficial effect GCF IL-10 and IL-17 A levels in severe periodontitis patients.
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Quantitative Multi-Parameter MRI Evaluation of Hashimoto’s Thyroiditis Changes After Dietary Interventions
BACKGROUND Hashimoto’s thyroiditis is a common autoimmune disease. There are currently few studies utilizing multi-parametric magnetic resonance imaging (MRI) to investigate diffuse thyroid lesions such as Hashimoto’s thyroiditis. This study aims to explore the value of multi-parametric MRI in assessing the progression of Hashimoto’s thyroiditis. MATERIAL AND METHODS The study ultimately included 40 patients with…
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Randomized Cross-Over Analysis of the Influence of Nitrogen Multiple Breath Washout on Spirometry in Monitoring Lung Function in Patients With Cystic Fibrosis and Primary Ciliary Dyskinesia
BACKGROUND: When monitoring lung function in patients with Cystic Fibrosis (pwCF) and Primary Ciliary Dyskinesia (pwPCD), nitrogen multiple breath washout (N(2)MBW) is usually performed before spirometry to prevent forced expiratory maneuvers from altering N(2)MBW results. The N(2)MBW may affect spirometry if cooperation decreases after a long period of examination or due to prolonged oxygen inhalation.…
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Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind randomized controlled trial
CONCLUSIONS: The expression of these biomarkers indicates that simvastatin is effective in reducing inflammation and pain in teeth with pulpal necrosis and symptomatic apical periodontitis when used as an intracanal medicament compared to Ca(OH)₂.