Clinical Trials
Category Added in a WPeMatico Campaign
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Development and evaluation of an intervention package to alleviate the psychological effects of premenstrual syndrome in adolescent girls
CONCLUSION: The findings demonstrate that a therapeutic package integrating CBT, Narrative Therapy, and cultural sensitivity can effectively alleviate PMS-related psychological symptoms in adolescent girls. This approach holds promise for broader applications in educational and counseling settings to enhance adolescent well-being.
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Impact of arm position on low dose dual-source CT one-step aortic and cerebral-carotid artery angiography image quality and radiation dose
CONCLUSION: Low-dose dual-source one-stop cerebral carotid aortic CTA radiation dose can be minimized and image quality can be improved by positioning both arms on the body side.
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Impact of spiritual care program on self-efficacy and burden in mothers of children with leukemia
CONCLUSION: Spiritual care program based on the Sound heart model improves self-efficacy and decreases caregivers’ burden in mothers of children with Leukemia. The use of this model is recommended for addressing the spiritual needs of mothers with children diagnosed with leukemia and for guiding health professionals in developing spiritual and healing care programs in clinical…
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Association of predicted lean body mass and fat mass with prognosis in patients with heart failure preserved ejection fraction
CONCLUSION: In patients with HFpEF, a higher FMI was strongly associated with increased risks of both the primary endpoint and all-cause mortality, while an elevated LBMI was associated with a reduced risk of mortality.
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Educational video combined with augmented clinical support to improve CPAP use in patients with obstructive sleep apnea-hypopnea syndrome: A randomized controlled trial protocol
CONCLUSION: We designed this original protocol by combining TPE with ACS. We hope that our findings will help us improve CPAP adherence among Tunisian patients with OSAHS.
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Initiating Injectable Buprenorphine in People Hospitalized With Infections: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial comparing initiation of LAB for OUD with ID management in the hospital setting compared with TAU, there was no difference between arms in the receipt of MOUD at 12 weeks. The TAU arm had higher retention than anticipated. These findings suggest that hospitalization with an infection related…
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A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease and coronary artery aneurysms
CONCLUSIONS: We found that atorvastatin was safe and a dose up to 0.5 mg/kg/day for 6 weeks was well-tolerated in Japanese children with acute KD and CAAs.
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Neuroprotective Activity of Rasayana Formulation and Effect of Shigru Pallava Eye Drops on Intraocular Pressure as an Add-on Therapy Compared to the Standard of Care in Primary Open-Angle Glaucoma: Protocol for an Exploratory, Open-label, Two-arm Randomized Controlled Trial
CONCLUSIONS: If shown to be effective, the combined RF and SP eye drops could enhance neuroprotection and further control IOP in POAG, thereby addressing a significant need in current glaucoma therapy. This trial may provide a foundation for larger-scale investigations into integrative treatments for glaucoma management.
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Outcomes of autologous bone marrow mononuclear cell administration combined with educational intervention in the treatment of autism spectrum disorder: a randomized, open-label, controlled phase II clinical trial
CONCLUSIONS: Intrathecal BMMNC combined with an educational intervention improved disease severity and adaptability more than education alone in children with ASD.
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Effect of esketamine on postinduction hypotension in elderly patients undergoing elective noncardiac surgery: a secondary analysis of a randomized clinical trial
Postinduction hypotension (PIH) increases the risk of perioperative adverse events. This study aimed to test if low-dose esketamine could significantly decrease the incidence of PIH in elderly patients undergoing elective noncardiac surgery. This was a post hoc analysis of a randomized clinical trial in university-affiliated academic tertiary hospital. Patients (65 to 85 years, ASA physical…