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8 Predictions for 2026
For as long as I (Max) can remember, I’ve intentionally used the holidays to reflect and write my predictions for the future. This year, AI is a dominant theme, but how can it not be? It’s one of the biggest platform shifts in history. It’s still early, so it should only get even more exciting… →
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Safety of a cytomegalovirus-specific hyperimmunoglobulin in the prevention of maternal-fetal transmission after primary infection-results of an open-label, single-arm, prospective trial
CONCLUSION: Despite a favorable safety profile, the benefit of treatment with CMVIG to prevent a maternal-fetal CMV transmission could not be demonstrated in our trial. →
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The effect of sleep hygiene education on sleep quality and blood pressure in patients with essential hypertension in a family practice center: a randomized controlled trial
CONCLUSIONS: Sleep hygiene education delivered in a primary care setting significantly improved sleep quality and reduced blood pressure levels in patients with essential hypertension. This approach may also help prevent complications related to hypertension. Clinical trial registration: ClinicalTrials.gov (Identifier: NCT07257237; registered on 20 November 2025). →
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Dexketoprofen Time-Dependent Administration After Third Molar Extraction: A Pilot Randomized Cross-Over Controlled Trial
CONCLUSIONS: Daytime administration of NSAIDs might be sufficient to manage postoperative pain after third molar extraction, and complications were similar between both groups. →
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Long-term effects of mentalization-based treatment for psychotic disorder: a 5-year follow-up of a multi-center, randomized-controlled trial
CONCLUSION: The results suggest a durable effect of MBTp. →
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Impact of Family-Centred Care Combined With Psychological Intervention on Sleep Quality and Psychological Status in Children With Bronchopneumonia: A Controlled Trial
CONCLUSION: FCC combined with psychological intervention effectively enhances sleep quality, mitigates anxiety, promotes treatment adherence and improves family satisfaction among children with bronchopneumonia. This provides practical evidence for the application of this comprehensive nursing model in paediatric clinical practice and research in the field of family-centred comprehensive interventions. →
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Multidimensional impact analysis of interactive video health intervention on quality of life and clinical rehabilitation indicators in patients with early postoperative bowel obstruction: a randomized controlled trial
CONCLUSION: The disease-specific QoL scale is valid for assessing patients with early postoperative bowel obstruction. The interactive video health intervention effectively improves their QoL and clinical rehabilitation, providing a feasible clinical tool. →
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AI-enabled electrocardiogram alert for potassium imbalance treatment: a pragmatic randomized controlled trial
Life-threatening dyskalemia, defined as an abnormal serum potassium concentration, is common in emergency settings that requires timely recognition and treatment and can be detected via AI-enabled electrocardiography. We conducted a pragmatic, open-label, randomized controlled trial with physician-level randomization to evaluate whether a real-time AI-enabled electrocardiography alert could improve physicians’ management of dyskalemia. Over a six-month… →
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Use of claims data to identify adverse events after colonoscopy in a randomised colorectal cancer screening trial in Norway: a cross-sectional study
CONCLUSIONS: Use of claims data underestimated adverse event rates following colonoscopy. Difference in coding practice across hospitals underscores the need for standardised reporting in screening programmes. →
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Effects of upadacitinib or adalimumab on pain in rheumatoid arthritis and psoriatic arthritis: results from randomised phase 3 studies
CONCLUSIONS: Upadacitinib effectively reduced pain in active RA and PsA, including in patients with AoI. The greater pain relief observed in RA with upadacitinib versus adalimumab might indicate both direct (relieving non-inflammatory pain) and indirect (suppressing inflammation) effects. →
