CONCLUSIONS: In patients with COPD, BDP/FF/G provided significant and clinically relevant improvements vs. placebo and BDP/FF in static and dynamic hyperinflation, with an improvement vs. placebo in exercise endurance. →
Omni-modality language models (OLMs) are a rapidly advancing area of AI that enables understanding and reasoning across multiple data types, including text, audio, video, and images. These models aim to simulate human-like comprehension by processing diverse inputs simultaneously, making them highly useful in complex, real-world applications. The research in this field seeks to create AI… →
Large language models (LLMs) have revolutionized how machines process and generate human language, but their ability to reason effectively across diverse tasks remains a significant challenge. Researchers in AI are working to enable these models to perform not just language understanding but also complex reasoning tasks like problem-solving in mathematics, logic, and general knowledge. The… →
Large Language Models (LLMs) have gained significant traction in recent years, with fine-tuning pre-trained models for specific tasks becoming a common practice. However, this approach needs help in resource efficiency when deploying separate models for each task. The growing demand for multitask learning solutions has led researchers to explore model merging as a viable alternative.… →
Multimodal AI models are powerful tools capable of both understanding and generating visual content. However, existing approaches often use a single visual encoder for both tasks, which leads to suboptimal performance due to the fundamentally different requirements of understanding and generation. Understanding requires high-level semantic abstraction, while generation focuses on local details and global consistency.… →
Maintaining the model’s capacity to manage changes in data distribution, i.e., the ability to function effectively even when presented with data that is different from what it was trained on, is essential when modifying a pre-trained foundation model for certain downstream tasks. Because retraining the entire model for each new dataset or task can be… →
CONCLUSIONS: We report a tailorable, patient-focused approach to identify drivers of research engagement in clinical research. Clinical trials offer an opportunity to collate a substantial evidence base on determinants of research participation and to identify context-specific factors. Results from the MEL-SELF trial emphasized notable altruism, self-empowerment, and perceived advantages of teledermatology as specific motivators. These… →
CONCLUSIONS: Tourniquet use during ACL reconstruction does not improve intraoperative visualization and does not reduce surgical time but leads to greater postoperative pain with a risk of well-known tourniquet-related complications. →