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  • Effectiveness of an 8-week neck exercise training on pain, jaw function, and oral health-related quality of life in women with chronic temporomandibular disorders: a randomized controlled trial

    10 января, 2025

    To test the effectiveness of an 8-week exercise program targeted to the neck muscles compared to manual therapy, and placebo treatments on orofacial pain intensity, jaw function, oral health-related quality of life (OHRQoL), and jaw range of motion (ROM) in women with Temporomandibular Disorders (TMD). In this randomized controlled trial, fifty-four women (between 18-45 years… →

    Clinical Trials
  • Effects of White Noise Intervention on Sleep Quality and Immunological Indicators of Patients with Breast Cancer Undergoing Neoadjuvant Chemotherapy

    10 января, 2025

    CONCLUSION: White noise intervention can improve the sleep quality of the NAC population with breast cancer and reduce the incidence of adverse reactions. In addition, it has no effect on the treatment efficacy, safety and immune indicators of patients. →

    Clinical Trials
  • Evaluating the effects of time-restricted eating on overweight and obese women with polycystic ovary syndrome: A randomized controlled trial study protocol

    10 января, 2025

    BACKGROUND: Time-restricted eating (TRE) manages weight effectively, but choosing how long and what time window remain debatable. Although an 8:00 a.m. to 16:00 p.m. time frame is reported to show positive results in most weight loss trial, its safety and efficacy in overweight and obese women with polycystic ovary syndrome (PCOS) is uncertain. This randomized… →

    Clinical Trials
  • Self- versus clinician-collected swabs in anal cancer screening: A clinical trial

    10 января, 2025

    CONCLUSIONS: SCA may be an acceptable and feasible alternative to CCA for detecting HPV and cytological abnormalities in a clinic population. →

    Clinical Trials
  • Meet KaLM-Embedding: A Series of Multilingual Embedding Models Built on Qwen2-0.5B and Released Under MIT

    10 января, 2025

    Multilingual applications and cross-lingual tasks are central to natural language processing (NLP) today, making robust embedding models essential. These models underpin systems like retrieval-augmented generation and other AI-driven solutions. However, existing models often struggle with noisy training data, limited domain diversity, and inefficiencies in managing multilingual datasets. These limitations affect performance and scalability. Researchers from… →

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  • Sudden gains in the treatment of children and adolescents with prolonged grief

    10 января, 2025

    CONCLUSIONS: Sudden gains seem to be a rare event with limited clinical relevance in the treatment of PGD symptoms in children and adolescents. Results imply future research into predictors of sudden gains and other forms of symptom change during PGD treatment. (PsycInfo Database Record (c) 2025 APA, all rights reserved). →

    Clinical Trials
  • Mediators of a randomized controlled trial of a preventive intervention for youth of parents with depressive disorders

    10 января, 2025

    CONCLUSIONS: This study provides clear and strong evidence that changes in youth SCC skills mediated the long-term effects of preventive intervention for families of depressed parents. (PsycInfo Database Record (c) 2025 APA, all rights reserved). →

    Clinical Trials
  • Biomarkers

    10 января, 2025

    CONCLUSION: Our findings confirmed the utility of our established AD pro-inflammatory endophenotype for use in the DS population. We demonstrate that a protein algorithm encompassing markers related to inflammation and neuropathology can be used to generate a predictive biomarker endophenotype that can identify DS participants who are more likely to respond and benefit from anti-inflammatory… →

    Clinical Trials
  • Biomarkers

    10 января, 2025

    CONCLUSION: As reported in Mohs et al. (2024), progression on the primary clinical/cognitive endpoint of the Clincial Dementia Rating Scale Sum of Boxes score (CDR-SB) occurred over the 78-week protocol in the HOPE4MCI study and non-carriers of ApoE4 treated with AGB101 showed a substantially more favorable effect than carriers. Here we report that treatment with… →

    Clinical Trials
  • Public Health

    10 января, 2025

    CONCLUSION: This study confirms the feasibility of training primary care physicians (PCPs) for the early detection, treatment, and support of individuals with dementia and their families. →

    Clinical Trials
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