Reinforcement Learning RL trains agents to maximize rewards by interacting with an environment. Online RL alternates between taking actions, collecting observations and rewards, and updating policies using this experience. Model-free RL (MFRL) maps observations to actions but requires extensive data collection. Model-based RL (MBRL) mitigates this by learning a world model (WM) for planning in… →
CONCLUSIONS: Although the combined ABM and CBT intervention did not result in statistically significant reductions in relapse risk and cravings compared to CBT alone, the overall reduction in these outcomes in both groups highlights the effectiveness of CBT in treating AUD. Future studies should use naturalistic settings and tailor the intervention to individual cognitive profiles. →
CONCLUSION: The Vitagnus-soy combination was more effective in alleviating PMS psychological and total symptoms than using either Soy or Vitagnus alone, making it a recommended option for reducing PMS symptoms.Trial Registration Number: IRCT2022072005514N. →
CONCLUSIONS: Adjunctive D-cycloserine with iTBS is a promising strategy to reduce suicidal ideation and implicit suicide risk in depression. →
CONCLUSIONS: Treatment with upadacitinib demonstrated consistent improvement and maintenance of treatment effect across efficacy endpoints through 2 years; no new safety signals were identified with additional exposure. →
CONCLUSION: Understanding the needs of youth experiencing homelessness who are at risk for suicide is critical to developing interventions to alleviate their risk for suicide. Given that the use of medical and mental health care is low among this population, more active outreach strategies may be warranted to deliver prevention interventions. →
BACKGROUND: Patients with advanced gastric cancer (AGC) have poor survival after first-line treatment containing an anti-programmed death-1/ligand 1 (PD-1/PD-L1) antibody. Accumulating evidence suggests rationales for continuing immunotherapy beyond progression, synergistic effects between immune checkpoint inhibitors and angiogenesis inhibitors, and a preferable combination of steroid-free chemotherapy with immunotherapy. These rationales imply that nanoparticle albumin-bound (nab)-paclitaxel… →
As we step into 2025, open-source projects continue to set new benchmarks in innovation and accessibility. This January, several GitHub repositories have emerged as trendsetters, ranging from personal AI assistants to advanced web automation tools and collaborative knowledge platforms. These projects highlight the incredible potential of community-driven development to solve real-world challenges. PROJECT #1 STORM:… →
CONCLUSIONS: Impaired left ventricular diastolic function, measured using tissue Doppler echocardiography through e’ and E/e’, independently predicts increased cardiovascular mortality over 20 years in hypertensive patients, highlighting its long-term prognostic significance. →
Despite recent advancements, generative video models still struggle to represent motion realistically. Many existing models focus primarily on pixel-level reconstruction, often leading to inconsistencies in motion coherence. These shortcomings manifest as unrealistic physics, missing frames, or distortions in complex motion sequences. For example, models may struggle with depicting rotational movements or dynamic actions like gymnastics… →