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Calm: The Underrated Capability Every Leader Needs Now
Chris Gash As companies push for greater productivity, an uncomfortable truth is emerging: Many employees no longer have the capacity to keep up. Leaders describe the same pattern everywhere — too many meetings, too little time to think, constant digital interruption, and a pace that leaves no room for recovery. Beneath these symptoms lies a… →
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Functional and cosmetic advantages of gasless endoscopic thyroidectomy in papillary thyroid carcinoma: a randomized trial
CONCLUSION: Compared with OP, ESSA is equally safe and effective, but more cosmetic and conducive to preserving functions of the anterior cervical region. ESSA can be considered an alternative approach to OP in hemithyroidectomy and CND. →
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Pilot Clinical Trial of Fecal Microbiota Transplantation for Constipation in Parkinson’s Disease
The purpose of this study was to evaluate the safety and efficacy of fecal microbiota transplantation in patients with constipation due to parkinson’s disease. Gut dysbiosis has long been associated with parkinson’s and recent studies have shown that FMT can restore the normal flora of the gut. Therefore, this clinical trial aimed to test the… →
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Effects of Chinese pediatric therapeutic massage on the management of functional constipation in children: A randomized single blind trial
CONCLUSION: Chinese pediatric Tuina therapy significantly improved FC symptoms caused by food stagnation with interior heat/inflammation in the studied population, with Han’s style having certain advantages. The Chinese Tuina therapy used in the study could be recommended as an alternative management approach for FC in children. →
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Weizmannia coagulans BC01 supplementation improved functional constipation by regulating gut microbiota: A randomized, placebo-controlled, clinical study
CONCLUSION: Current evidence supports the use of BC01 as a therapeutic option for managing functional constipation. →
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Sirtuins and regulatory miRNAs as epigenetic determinants of empagliflozin-mediated recovery after acute myocardial infarction
CONCLUSION: Baseline levels of SIRT2, SIRT4, miR-182-5p, and miR-302a-3p were identified as predictors of ΔLVEF < 11% changes after 26-weeks of treatment, which suggests their potential for stratifying responders and non-responders to empagliflozin. The combined panel of these markers demonstrated the highest predictive accuracy, suggesting the epigenetic influence of SGLT2 inhibitors and the potential for… →
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A novel antituberculosis agent exhibits potent clinical efficacy and good safety profile: an open-label, randomized-controlled, multicenter, phase 2a trial
Tuberculosis (TB) is a contagious disease that threatens human health worldwide. Combination chemotherapy is usually recommended for this disease. Recently, 2 nitroimidazole-based agents, namely, delamanid and pretomanid, have been approved by regulatory agencies. JDB0131 is a novel, structurally optimized third-generation nitroimidazole antituberculosis agent that incorporates the advantages of earlier compounds. This multicenter, prospective, randomized phase… →
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The Top Five MIT SMR Videos of 2025
Our most-watched video of the year took on a tough topic: the hype surrounding artificial intelligence. MIT economist and Nobel laureate Daron Acemoglu grabbed readers’ attention with his no-nonsense take on what AI will and won’t do to the modern economy and employment — earning hundreds of thousands of views and sparking a spirited discussion… →