An M1/M2 macrophage-regulating treatment, ON101 cream, has shown its superior healing efficacy for diabetic foot ulcers (DFUs) versus standard absorbent dressing, according to a phase III trial. Given its high cost, corroborating the economic value of ON101 treatment can facilitate clinical and policy decision-makings. This study sought to evaluate the cost-effectiveness of ON101 versus an… →

CONCLUSIONS: The results indicate that Sterimar soothing nose cream is effective in nourishing, soothing, protecting, and moisturizing the nasolabial zone, and is well tolerated. →

CONCLUSIONS: Stockholm3 outperforms other commonly used biomarkers and risk calculators for detecting GG ≥ 2 cancer in a diverse population. →

CONCLUSIONS: Our findings support the short-term use of folate as a beneficial adjunct in treating acute manic episodes in bipolar I disorder. However, the addition of vitamin B6 did not yield additional advantages. These results may inform future treatment guidelines targeting acute mania in bipolar disorder, advocating for folate supplementation as a potential strategy to… →

Aficamten is a next-in-class, small-molecule, cardiac myosin inhibitor in development for treating hypertrophic cardiomyopathy (HCM). This 2-part study evaluated aficamten’s impact on QTc interval in healthy participants. Part A (n = 10) was an open-label study to find the appropriate dose for thorough QT (TQT) evaluation in Part B. Part B (n = 34) was… →

CONCLUSIONS: Our findings suggest that AI-integrated interventions like GymBuddy and Elomia may serve as effective tools for reducing psychological distress in student populations. Integrating AI technology into mental health interventions offers personalized support and guidance, addressing a crucial need in student populations. Further research is warranted to explore long-term outcomes and optimize the implementation of… →

CONCLUSION: Tele-nursing after discharge caused a significant decrease in anxiety and increased self-efficacy of mothers in taking care of their children; therefore, it is recommended to use a comprehensive program in the form of tele-nursing according to parents’ educational needs and wishes. →

The formation mechanism of OLP is very complicated, and its treatment has always been a difficult problem. This study was to explore the feasibility of pulsed Er: YAG laser in the treatment of erosive OLP by comparing its effect with that of Triamcinolone Acetonide ointment(TA) of OLP, in order to provide new ideas for the… →