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An App-Based WHO Mental Health Guide for Depression Detection: A Cluster Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: This feasibility cluster randomized clinical trial demonstrated that the use, cost, and potential clinical benefit of the e-mhGAP-IG varied by setting, highlighting the importance of multisite feasibility studies when evaluating digital innovations intended for health care systems worldwide. →
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Efficacy of a 1% ibuprofen nanostructured topical gel in reducing in-office bleaching sensitivity following 35% hydrogen peroxide application: a randomized, controlled, triple-blind, split-mouth clinical trial
CONCLUSION: The novel 1% ibuprofen nanostructured topical gel was ineffective in reducing BS and did not affect tooth color change. →
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Exploring Neurobiological Effects of Intermittent Theta-Burst Stimulation on the Left Cerebellum for Post-stroke Unilateral Neglect: A Preliminary Transcranial Magnetic Stimulation-Electroencephalography Investigation
Unilateral neglect (UN) is a frequent consequence of stroke, for which effective therapeutic interventions are yet to be definitively established. This study aims to assess the therapeutic potential of intermittent theta-burst stimulation (iTBS) applied to the contralesional cerebellum in reducing UN symptoms. Additionally, it seeks to clarify the neurophysiological mechanisms involved, thereby supporting the development… →
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Clinical and radiographic evaluation of Er: YAG laser-assisted direct pulp capping in permanent teeth with carious exposure
CONCLUSION: The inclusion of Er: YAG laser in DPC procedures enhances treatment outcomes, particularly when combined with Biodentine. This approach offers a promising alternative for vital pulp therapy in mature permanent teeth, ensuring better dentin bridge formation and clinical success. →
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Advancing dementia preparedness in Low and Middle Income countries: A randomized trial to improve diagnosis in primary care
INTRODUCTION: Dementia disproportionately affects individuals in low- and middle-income countries (LMICs), yet diagnostic capabilities there are often inadequate. This study assesses the impact of a structured training program for primary care physicians (PCPs) in Cuba to improve early dementia detection. →
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The impact of Limosilactobacillus reuteri in combination with non-surgical periodontal therapy on periodontal clinical parameters and salivary and subgingival microbiota composition in individuals with stage III-IV periodontitis: a randomized controlled trial
CONCLUSIONS: Combining L. reuteri with non-surgical periodontal therapy may not directly improve clinical indicators. The treatment showed potential benefits by changing the microbial composition of subgingival biofilm and enhancing treatment sensitivity. →
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Efficacy and safety of prophylactic simultaneous intravitreal moxifloxacin injection with standard intravitreal anti-VEGF injection procedure in cases of cystoid macular edema and macular neovascularization
CONCLUSION: Simultaneous intravitreal injection of moxifloxacin during intravitreal anti-VEGF procedure is safe and effective measure to be added to the armamentarium of prophylaxis against post injection endophthalmitis. →
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Researchers from the National University of Singapore Introduce ‘Thinkless,’ an Adaptive Framework that Reduces Unnecessary Reasoning by up to 90% Using DeGRPO
Introducing ‘Thinkless’: An Adaptive Framework for Efficient Language Model Reasoning Researchers from the National University of Singapore have developed a new framework known as Thinkless, designed to enhance the efficiency of language models by reducing unnecessary reasoning by up to 90%. This framework addresses a core challenge in current language models, where extensive reasoning processes… →
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Researchers Introduce MMLONGBENCH: A Comprehensive Benchmark for Long-Context Vision-Language Models
Researchers Introduce MMLONGBENCH: A Comprehensive Benchmark for Long-Context Vision-Language Models Recent advances in long-context (LC) modeling have significantly enhanced the capabilities of large language models (LLMs) and large vision-language models (LVLMs). Long-context vision-language models (LCVLMs) are now capable of processing hundreds of images and thousands of interleaved text tokens in a single forward pass. However,… →
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The Surprising Viability of the Four-Day Workweek
Alexis Franklin Is the shift to a four-day workweek a real movement, a post-pandemic fad, or a pipe dream? In her new book, Four Days a Week: The Life-Changing Solution for Reducing Employee Stress, Improving Well-Being, and Working Smarter (Harper Business, June 2025), Juliet B. Schor, an economist and sociologist at Boston College, sheds light… →