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  • Enhanced external counter pulsation as a novel therapy to maintain cardiac output during hemodialysis: a preliminary randomized controlled study

    9 октября, 2025

    Intradialytic cardiac output (CO) decline normally occurs during hemodialysis (HD) and results in short-term intradialytic hypotension to longer-term increased cardiovascular morbidity and mortality in chronic HD patients. Enhanced external counter pulsation (EECP) is a novel non-invasive device that has been demonstrated to improve coronary blood flow and maintain systemic hemodynamics in patients without kidney dysfunction.… →

    Clinical Trials
  • Cost analysis of integrating depression treatment into chronic care in Malawi: evidence from a cluster randomised controlled trial

    9 октября, 2025

    CONCLUSIONS: These findings indicate that integrating depression care services into the Malawian health system is financially feasible and successfully reached many individuals with major depressive disorder. →

    Clinical Trials
  • Effect of prophylactic fibrinogen concentrate in scoliosis surgery (EFISS): a randomised pilot trial

    9 октября, 2025

    CONCLUSIONS: This study demonstrates that the prophylactic administration of fibrinogen during scoliosis surgery in children is feasible and appears to be safe. Due to the limited sample size, no conclusions can be drawn regarding the efficacy of pre-emptive fibrinogen administration on clinical outcomes. However, the results provide valuable data to inform sample size calculation for… →

    Clinical Trials
  • RA3: Mid-Training with Temporal Action Abstractions for Faster Reinforcement Learning (RL) Post-Training in Code LLMs

    9 октября, 2025

    RA3: Mid-Training with Temporal Action Abstractions for Faster Reinforcement Learning (RL) Post-Training in Code LLMs The recent research from Apple formalizes the concept of “mid-training” and its impact on reinforcement learning (RL) post-training. This study introduces RA3 (Reasoning as Action Abstractions), an iterative procedure that enhances model training through the following strategies: 1. Pruning to… →

    AI News
  • Why Agency Helps Employees Cope With Change

    9 октября, 2025

    Marie Montocchio/Ikon Images Workplace developments like hybrid working and artificial intelligence have brought a cascade of sometimes destabilizing changes that many people have struggled to keep up with. Such changes can leave employees feeling as if the rug has been pulled out from under them. How can leaders stop change from undermining workers’ morale and… →

    Management
  • Stanford Researchers Released AgentFlow: In-the-Flow Reinforcement Learning RL for Modular, Tool-Using AI Agents

    9 октября, 2025

    «`html Stanford Researchers Released AgentFlow: In-the-Flow Reinforcement Learning for Modular, Tool-Using AI Agents Understanding the Target Audience The target audience for AgentFlow primarily includes AI researchers, business leaders in technology, and developers interested in advanced AI applications. These individuals are typically well-versed in machine learning concepts and seek innovative solutions to enhance AI capabilities in… →

    AI News
  • Dipsticks and point-of-care Microscopy in Urinary Tract Infections in primary care: Results of the MicUTI pilot cluster randomised controlled trial

    9 октября, 2025

    CONCLUSION: The POCT-guided management approach for suspected uUTIs is feasible but presents implementation and methodological challenges. Recruitment varied across sites and was lower in the control group practices, highlighting the risk of differential recruitment. Retention was below the expected 80%, indicating the need for efficient follow-up strategies in future trials. Explorative analyses suggest that simply… →

    Clinical Trials
  • Effect of a digital tool on breast cancer specific health-related quality of life and psychological distress: secondary results from the ADAPT study

    8 октября, 2025

    CONCLUSION: The breast cancer digital tool did not have a significant effect on breast cancer-specific HRQoL and psychological distress over time. The results are consistent with the findings of the primary ADAPT paper, which demonstrated that the digital tool did not have a significant effect on patient activation, HRQoL, and health status. There is a… →

    Clinical Trials
  • Anthropic AI Releases Petri: An Open-Source Framework for Automated Auditing by Using AI Agents to Test the Behaviors of Target Models on Diverse Scenarios

    8 октября, 2025

    Anthropic AI Releases Petri: An Open-Source Framework for Automated Auditing Understanding the Target Audience The primary audience for this release includes AI researchers, business leaders in tech, compliance officers, and developers interested in AI alignment and safety. Their pain points revolve around ensuring the ethical use of AI, managing risks associated with misaligned behaviors, and… →

    AI News
  • Efficacy of Stapled Haemorrhoidopexy vs. Ferguson Haemorrhoidectomy in the Treatment of Haemorrhoidal Disease: A Prospective, Randomised, Single-Blind Comparison

    8 октября, 2025

    CONCLUSION: SH was equally effective as FH in controlling symptoms associated with HD in the postoperative period and may be recommended as a minimally invasive treatment option for patients. →

    Clinical Trials
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