CONCLUSION: The EBRFA, when combined with SEMS placement, demonstrated procedural feasibility and acceptable outcomes as a potential palliative approach for patients with unresectable pCCA. →

«`html ByteDance Just Released Trae Agent: An LLM-based Agent for General Purpose Software Engineering Tasks ByteDance, the Chinese tech giant behind TikTok and other global platforms, has officially released Trae Agent, a general-purpose software engineering agent powered by large language models (LLMs). Designed to execute complex programming tasks via natural language prompts, Trae Agent offers… →
Getting Started with Agent Communication Protocol (ACP): Build a Weather Agent with Python Getting Started with Agent Communication Protocol (ACP): Build a Weather Agent with Python The Agent Communication Protocol (ACP) is an open standard designed to enable seamless communication between AI agents, applications, and humans. As AI systems are often developed using diverse frameworks… →
Understanding Limitations of Current Reward Models Although reward models are crucial in Reinforcement Learning from Human Feedback (RLHF), many of today’s top-performing open models struggle to reflect the full range of complex human preferences. Even with advanced training techniques, meaningful progress has been limited. A major reason for this is the shortcomings in current preference… →
«`html New AI Method From Meta and NYU Boosts LLM Alignment Using Semi-Online Reinforcement Learning Understanding the Target Audience The target audience for this research includes AI researchers, data scientists, business managers, and decision-makers in technology firms. Their pain points revolve around the challenges of aligning large language models (LLMs) with human expectations, optimizing model… →
This trial compared antithymocyte globulin (ATG) + cyclosporine A (CsA) + avatrombopag (AVA) and CsA + AVA in older adults with severe aplastic anemia (SAA). The patients were randomized to receive either ATG + CsA + AVA or CsA + AVA. Of 84 included patients, 42 were treated with ATG + CsA + AVA and… →

«`html What Is Context Engineering in AI? Techniques, Use Cases, and Why It Matters Introduction: What is Context Engineering? Context engineering refers to the discipline of designing, organizing, and manipulating the context that is fed into large language models (LLMs) to optimize their performance. This practice focuses on the input—the prompts, system instructions, retrieved knowledge,… →
A Coding Guide to Build Modular and Self-Correcting QA Systems with DSPy In this tutorial, we explore how to build an intelligent and self-correcting question-answering system using the DSPy framework, integrated with Google’s Gemini 1.5 Flash model. We begin by defining structured Signatures that clearly outline input-output behavior, which DSPy uses as its foundation for… →
«`html Chai Discovery Team Releases Chai-2: AI Model Achieves 16% Hit Rate in De Novo Antibody Design Chai Discovery Team introduces Chai-2, a multimodal AI model that enables zero-shot de novo antibody design. Achieving a 16% hit rate across 52 novel targets using ≤20 candidates per target, Chai-2 outperforms prior methods by over 100x and… →
CONCLUSIONS: N-ABT clinically improve clinical outcomes (> 20%) during the observation period, it also demonstrated enhanced filling quality and efficiency and reduced technical sensitivity. →
