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How RLI’s CEO Builds Agile Culture in a Conservative Industry
Aleksandar Savic RLI could have suffered the fate of Polaroid, Blockbuster, or BlackBerry, slipping into oblivion when market changes eroded demand for their core product. Founded 60 years ago as Replacement Lens Inc., the company insured the cost of replacing lost or damaged contact lenses — then an expensive purchase. As disposable lenses became the… →
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Oestrogen replacement combined with resistance exercise in older women with knee osteoarthritis: a randomised, double-blind, placebo-controlled clinical trial
CONCLUSIONS: ERT did not confer significant additive benefits to resistance exercise overall but may improve outcomes in early-stage KOA and mental health domains. These exploratory findings warrant further investigation. →
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GTM 158: From Startup to $4B+ Unicorn: How Vanta Scaled Past $100M ARR and Beat 40+ Competitors | Stevie Case
The GTM Podcast is available on any major directory, including: Apple Podcasts Spotify YouTube Stevie Case is the Chief Revenue Officer at Vanta, the $4B leader in trust management and compliance automation. Since joining in 2021, Stevie has scaled the company from sub-$20M ARR to north of $100M, navigated 40+ copycat competitors, rebuilt both pre-… →
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Minimal vs Specialized Exercise Equipment for Pulmonary Rehabilitation: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: This randomized clinical trial found that PR-min demonstrated noninferiority to PR-gym for exercise capacity, dyspnea, and health-related quality of life. PR-min can expand the number of settings where PR can be provided, thus improving patient accessibility. →
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NVIDIA AI Releases ProRLv2: Advancing Reasoning in Language Models with Extended Reinforcement Learning RL
NVIDIA AI Releases ProRLv2: Advancing Reasoning in Language Models with Extended Reinforcement Learning RL What Is ProRLv2? ProRLv2 is the latest version of NVIDIA’s Prolonged Reinforcement Learning (ProRL), designed specifically to push the boundaries of reasoning in large language models (LLMs). By scaling reinforcement learning (RL) steps from 2,000 up to 3,000, ProRLv2 systematically tests… →
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Factors associated with distress over time in women with breast cancer undergoing radiotherapy: insights from a pilot study assessing a digital information tool
CONCLUSION: The results indicate no statistically significant effect on distress; however, there is a potential indication of a reduction in distress, suggesting that the digital information tool may offer some benefits. Further research is required to confirm this relationship. →
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Effects of occupational therapy on hand function in patients with systemic sclerosis: a randomized controlled trial
Hand involvement is one of the most disabling features of systemic sclerosis (SSc). Although occupational therapy is frequently employed in rheumatic conditions, its particular effects in SSc have not been studied in detail yet. This study aimed to evaluate the impact of a structured three-week occupational therapy program on hand function in SSc. This randomized… →
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Association of Intraoperative Hypotension with Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery: A Secondary Analysis of a Randomized Trial
CONCLUSIONS: Intraoperative hypotension was not associated with PONV in patients at high risk of PONV who underwent laparoscopic gastrointestinal surgery. →
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Meet LEANN: The Tiniest Vector Database that Democratizes Personal AI with Storage-Efficient Approximate Nearest Neighbor (ANN) Search Index
«`html Meet LEANN: The Tiniest Vector Database that Democratizes Personal AI with Storage-Efficient Approximate Nearest Neighbor (ANN) Search Index Understanding the Target Audience The target audience for LEANN includes AI researchers, data scientists, and business professionals interested in implementing efficient AI solutions on personal devices. Their pain points often revolve around the high storage overhead… →
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Spinal Anaesthesia Versus General Anaesthesia for Patients With Tibia Shaft Fractures-A Randomized Controlled Study
CONCLUSION: Spinal anaesthesia was not associated with higher compartment pressures compared to general anaesthesia. These findings suggest that prevailing concerns and recommendations about spinal anaesthesia for tibia shaft fracture surgery may need reconsideration and challenge recommendations favouring general anaesthesia as the primary method. →
