Clinical Trials
Category Added in a WPeMatico Campaign
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The effects of povidone-ıodine and chlorhexidine gluconate on the ocular surface after phacoemulsification cataract surgery
CONCLUSION: Both PI and CHG caused transient ocular surface changes after cataract surgery. However, CHG demonstrated faster recovery of tear film parameters and improved early postoperative comfort, suggesting it may be a preferable antiseptic in patients with ocular surface sensitivity.
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Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT
CONCLUSIONS: We found no evidence that completion of the development and well-being assessment aided the detection of emotional disorders in this study. Using the development and well-being assessment in this way cannot be recommended for clinical practice.
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Procedural characteristics and clinical outcomes from same-day discharge after pulsed field ablation treatment for atrial fibrillation: an admIRE trial sub-analysis
CONCLUSION: SDD is feasible in a paroxysmal AF population undergoing PFA with the VLCC, demonstrating comparable safety and effectiveness outcomes with overnight hospitalization.
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Application and Efficacy Evaluation of a Modified Ostomy Appliance in Managing Peristomal Irritant Contact Dermatitis: A Randomised Controlled Trial
Irritant contact dermatitis is a common peristomal skin complication. Due to the continuous irritation from intestinal fluids and faeces, the healing of this dermatitis is slow and the condition severely impairs patients’ quality of life. The study aimed to evaluate the efficacy of a modified insertable ostomy appliance in promoting healing and improving patient outcomes.…
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Perceived health, musculoskeletal disorders, work conditions and safety climate in relation to patient handling and movement - a multicentre cross-sectional study at healthcare workplaces
CONCLUSIONS: Substantial physical and organizational challenges related to PHM were reported by HCWs across both care contexts. The findings suggest that interventions emphasizing leadership engagement, a systematic approach to training, and tailored solutions are essential to strengthen the safety climate and reduce HCWs’ health risks.
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Group-Based Relational Savoring Intervention in Mothers of Young Children in Iran: Testing Impacts of Memory Type
Relational savoring, a prevention/intervention approach that involves reflecting on positive moments of connection with another person, promotes wellbeing in the parenting relationship. In this program, parents savor memories with strong attachment content (including Secure Base or Safe Haven memories), but it is currently unknown whether the benefits of relational savoring differ as a function of…
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Ten-year target lesion failure in patients treated with primary PCI: results from DANAMI-3
CONCLUSIONS: One in five STEMI patients treated with primary PCI experiences TLF within 10 years, accounting for a significant proportion of any mortality, any MI or any revascularisation, with sustained occurrence rates beyond the first year.
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Cost-effectiveness of a technology-assisted peer-delivered perinatal mental health intervention in Pakistan: an economic evaluation using trial evidence
CONCLUSIONS: Our analysis suggests that THP-TAP could represent a scalable, health-improving and cost-saving intervention to support those with perinatal depression, when compared with WHO-THP.
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Perceived effectiveness of messages to address cervical cancer screening barriers: An online experiment
CONCLUSIONS: Messages targeting known barriers to cervical cancer screening were perceived as more effective than a control message. These messages could increase cervical cancer screening rates if used in interventions at scale.
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Quality Improvement Intervention to Increase Sleep Apnea Diagnostic Testing After Stroke and Transient Ischemic Attack: A Cluster Randomized Trial
CONCLUSIONS AND RELEVANCE: In this cluster randomized trial of patients with acute cerebrovascular events, quality improvement approaches increased OSA testing. These results suggest that health care systems can improve the delivery of guideline-concordant care for patients with acute ischemic stroke and TIA by delivering inpatient sleep medicine services.