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BACKGROUND: Hypertension presents as a modifiable risk factor for cardiovascular diseases, with approximately two-thirds of the global hypertensive population concentrated in low- and middle-income nations. Sarpagandha Mishran is an Ayurveda intervention utilized for the management of hypertension. The objective of the study is to assess the clinical efficacy and safety of Sarpgandha Mishran in the…
Advancements in emergency medicine and critical care have significantly improved survival rates for patients with severe acquired brain injuries(sABI), subsequently increasing the prevalence of disorders of consciousness (DoC) such as Unresponsive Wakefulness Syndrome (UWS) and Minimally Conscious State (MCS). However, the assessment of conscious states relies on the observation of behavioral responses, the interpretation of…
CONCLUSIONS: DNS is superior to conventional core exercises in enhancing core muscle contractility and standing postural control in CLBP patients, showing potential to reduce pain and improve disability. Its mechanism may involve the enhancement of proprioceptive feedback, particularly when visual feedback is blocked.
CONCLUSIONS: The experimental 10% pregabalin gel reduced dental sensitivity and did not interfere with bleaching results.
CONCLUSION: We conclude that the application of Earmuff is a fruitful method for preterm neonates to improve and stabilize the physiological parameters and behavioral response.
Chronic Spontaneous Urticaria (CSU) significantly affects quality of life. This study evaluates the efficacy of histaglobulin combined with antihistamine (bilastine) versus antihistamine alone in CSU management. A single-center, open-label, randomized trial was conducted in the dermatology OPD of a tertiary care hospital from September 2023 to August 2024. Fifty-seven eligible participants aged > 18 years…
CONCLUSIONS: Task-oriented circuit training in conjunction with a designed physiotherapy program is more effective in improving gait kinematics, pelvic symmetry, and endurance of trunk muscles among children with hemiplegia.
OBJECTIVE: Postpartum hemorrhage (PPH) is the leading cause of maternal death. Identifying excessive bleeding is crucial, but there is no gold standard for its measurement. We aimed to assess accordance between two formulas for calculated blood loss (CBL) and weight-based blood loss (WBBL) to determine if CBL has a place in either the clinical or…
CONCLUSION: High PFKFB3 is associated with a larger reduction of IBTR after radiotherapy but PFKFB3 cannot reliably be used as a predictive marker of sensitivity to adjuvant radiotherapy in breast cancer. PFKFB3 expression differed with subtype, indicating that it may be a better marker among Luminal A and HER2 positive tumors, but this is yet…
CONCLUSIONS: The Friend chatbot offers a scalable, cost-effective solution for psychological support, particularly in crisis situations where traditional therapy may not be accessible. Although traditional therapy remains more effective in reducing anxiety, a hybrid model combining AI support with human interaction could optimize mental health care, especially in underserved areas or during emergencies. Further research…