Clinical Trials
Category Added in a WPeMatico Campaign
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Validity and usability for digital cognitive assessment tools to screen for mild cognitive impairment: a randomized crossover trial
CONCLUSIONS: Digital cognitive tests are valid and feasible in PHC settings but face implementation challenges, especially in usability and adaptability among individuals with lower education levels.
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Awareness of baseline functioning and sensitivity to improvement in older people with and without mild cognitive impairment receiving a computerized functional skills training program
CONCLUSIONS: Participants with MCI underestimated their performance deficits at baseline. Self-reports of changes in everyday functioning do not track the substantial objective changes. Previous studies have reported a lack of sensitivity to training gains in several different conditions. Strategies to increase awareness of training gains may be required to sustain treatment benefits.
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Systemic indocyanine green administration to detect bile leakage after liver surgery: a prospective clinical trial, using historical controls
CONCLUSIONS: Intraoperative ICG administration and assessment effectively lower bilirubin levels in drainage fluid during hepatectomy, potentially reducing the incidence of BL.
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Development and validation of a nomogram for predicting the clearance of jaundice in children with biliary Atresia after Kasai portoenterostomy
CONCLUSION: This study developed and validated a nomogram incorporating four indictors, including Age at KPE, postoperative AST level at two weeks, CR of DB at two weeks post-KPE and F-score at KPE, may be useful for predicting CJ at 3 months after KPE in children with BA.
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Efficacy of Action of Low-Temperature Plasma Radiofrequency Ablation in the Treatment of Early Glottic Carcinoma
CONCLUSION: Our findings demonstrate the successful application of low-temperature plasma radiofrequency ablation in the management of early glottic carcinoma. This innovative technique offers several potential advantages, including reduced intraoperative bleeding, shorter surgical duration, and hospital stay. Additionally, it promotes enhanced postoperative voice restoration and mucosal healing, while minimizing the occurrence of postoperative complications. These compelling…
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Effects of Music and Aromatherapy on Blood Pressure and Heart Rate Among Endodontic Patients: A Randomized Clinical Trial
CONCLUSIONS: Music and aromatherapy did not produce statistically significant reductions in blood pressure and heart rate among endodontic patients. Alternative methods should be explored to manage patient anxiety better.
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Impact of molar incisor hypomineralization on oral health-related quality of life, dental fear and anxiety in Swedish children
CONCLUSIONS: Restorative treatment and extraction of FPMs affected by MIH lead to similar impact on DFA and OHRQoL at 11 years of age.
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Lung cancer screening in Finland: a prospective randomized trial
BACKGROUND: Early detection of lung cancer with low-dose computed tomography (LDCT) screening can shift diagnoses to early-stage disease and improve survival. However, LDCT has several challenges such as high false positive rate and indefinite cost-effectiveness. We report here secondary and exploratory endpoints of the Low-dose CT screening for lung cancer combined with different smoking cessation…
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The effect of supportive care on mood, general health, competence on caregivers of cancer patients, and supportive care needs on cancer patients undergoing chemotherapy: a controlled clinical trial
CONCLUSION: The results of this study revealed that the supportive care program was effective in mood states, general health, competence of caregivers, and grade of supportive care needs of cancer patients undergoing chemotherapy.
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Screening and Care for Emotional and Cognitive Problems After Ischemic Stroke: Results of a Multicenter, Cluster-Randomized Controlled Trial
BACKGROUND AND OBJECTIVES: Evidence regarding effectiveness of screening for emotional and cognitive problems after stroke is lacking. The primary aim of this study was to test the hypothesis that an intervention focusing on screening and care for emotional and cognitive problems after stroke would improve societal participation at 1 year. Second, we tested the hypotheses…