Clinical Trials
Category Added in a WPeMatico Campaign
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SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial
CONCLUSIONS: In this novel trial, SMS text message and automated phone reminders were effective in promoting more timely HPV vaccination in this population.
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Clinical effects of stannous fluoride dentifrice on peri-implant mucositis, plaque microbiome, and oxidative stress
PURPOSE: This single-center, single-treatment, 4-week study evaluated the efficacy of a stannous fluoride (SnF₂) dentifrice in reducing peri-implant mucositis while assessing changes in biomarkers and the oral microbiome profile.
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Evaluation of tooth color, whiteness changes and sensitivity following laser-assisted in-office tooth bleaching using Er,Cr:YSGG laser: A prospective clinical study
PURPOSE: This prospective clinical study evaluated the tooth color (ΔΕ*ab and ΔΕ₀₀) and whiteness (ΔWID) changes, as well as tooth sensitivity (TS) induced after performing in-office tooth bleaching with or without light-activation of the bleaching gel using Er,Cr:YSGG laser irradiation.
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Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial
Activation of adenosine triphosphate-sensitive potassium (K ATP ) channels has been implicated in triggering migraine attacks. However, whether the opening of these channels provoke cluster headache attacks remains undetermined. The hallmark of cluster headache is a distinct cyclical pattern of recurrent, severe headache episodes, succeeded by intervals of remission where no symptoms are present. In…
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Effectiveness of Self-Training With a Web-Based Digital Health Application Versus Physiotherapy in the Treatment of Disorders of the Patella: Randomized Controlled Trial
CONCLUSIONS: Our findings indicated that the investigated DHA is superior to SHI-PT for treating disorders of the patella. Therefore, DHA has been approved by the German Federal Institute for Drugs and Medical Devices for treating disorders of the patella in persons of all sexes aged ≥12 years.
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Autologous mesenchymal stem cells as a component of multidisciplinary rehabilitation of war participants with severe forms of chronic critical lower limb ischemia and pain syndroms
CONCLUSION: Conclusions: The implementation of MRP, integrating MSCs therapy, led to significant improvements in pain relief, tissue regeneration and overall functional recovery in patients with CCLLI, particularly those with military-related injuries, favouring the reduction of the risk of lower limb amputation.
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The Effect of Chewing Gum in Managing Labor Pain Intensity and Anxiety Level in Primiparous Women: A Randomized Controlled Trial
CONCLUSION: Chewing gum is a practical alternative method for decreasing anxiety and pain intensity during childbirth in primiparous women.Trial Registration Number: IRCT20100510003902N5.
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A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial for the Efficacy and Safety of a Novel Nutraceutical for Mild-to-Moderate Acne
CONCLUSION: The oral nutraceutical significantly improves mild-to-moderate acne and overall skin health in adult women when compared to a placebo.
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Caffeine’s influence on vertical jump height: a real-life collegiate student-athlete approach
CONCLUSIONS: A 5 mg/kg caffeine dose, compliant with NCAA thresholds, did not enhance vertical jump performance in habituated collegiate athletes, challenging prior assertions of its universal ergogenicity for ballistic tasks. While sex differences in baseline performance persisted, caffeine did not modulate these disparities, implicating neuromuscular and anthropometric factors as primary determinants. The absence of ergogenic…
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Effectiveness of Nurse-Led Psychoeducation on Knowledge and Psychological Distress in Cancer Patients Undergoing Radiological Imaging: A Randomized Controlled Trial
CONCLUSION: Nurse-led psychoeducation effectively improved knowledge and reduced anxiety in patients with cancer undergoing radiological imaging. Integrating such interventions into pre-imaging protocols can enhance patient preparedness and reduce psychological distress. Further research should explore the long-term effects and adaptability of this intervention in diverse healthcare settings.