Clinical Trials
Category Added in a WPeMatico Campaign
-
Psychological intervention based on the extension and expansion of positive psychology model improves psychosexual resilience and erectile function in patients with psychogenic ED
CONCLUSION: For the treatment of pED, PERMA-based psychological intervention in addition to active medication contributes to elevating the psychological resilience and improving the erectile function of the patients.
-
Sertraline hydrochloride combined with compound chamomile lidocaine gel for the treatment of premature ejaculation
CONCLUSION: Sertraline hydrochloride combined with compound chamomile lidocaine gel is definitely effective in the treatment of PE, which can significantly improve the patients’ quality of sexual life, with a high safety and low incidence of adverse reactions.
-
Randomized controlled trial on the clinical efficacy of hernia needle combined with single port laparoscopic scrotal approach and testicular arch fixation for the treatment of middle and low cryptorchidism in children
CONCLUSION: HN-SLATO has a significant clinical efficiency and high safety in the treatment of mid-low cryptorchidism in children, which can effectively improve intraoperative fixation and postoperative aesthetics of the testis, as well as reduce pain, serum inflammatory indicators and postoperative complications.
-
Effects of high-protein nutritional supplementation on nutritional status, physical function, and quality of life in older gastric cancer patients receiving neoadjuvant chemotherapy: a randomized trial
CONCLUSIONS: High-protein ONS improved nutritional status and reduced malnutrition risk in older gastric cancer patients undergoing NAC. Further research is needed to assess the long-term effects of ONS on physical function and quality of life.
-
Successfully Reducing Sitting Time Can Improve Metabolic Flexibility
Impaired metabolic flexibility (MetFlex; the ability to regulate substrate oxidation) and sedentary behavior are both linked to cardiometabolic diseases, but the relationship between the two is not fully elucidated. This study investigated the effects of reduced sedentary time on MetFlex. Sixty-four sedentary adults with metabolic syndrome were randomized into intervention (INT, n = 33) and…
-
Beyond the splint: efficacy and safety of kinesio taping for non-operative management of finger injuries
BACKGROUND: This prospective comparative study aimed to evaluate the efficacy of kinesio-taping (KT), buddy taping (BT), and conventional splinting in managing finger joint sprains and fractures across pediatric and adult populations, with a focus on functional recovery and patient-centered outcomes.
-
The efficacy and safety of hydroxychloroquine in patients with chronic inflammatory cardiomyopathy: a multicenter randomized study (HYPIC trial)
CONCLUSIONS: Twelve months of HCQ combined with PDN therapy significantly improved the prognosis and heart function, inhibited inflammation, and had acceptable safety in patients with infl-CMP after FM.
-
Cost-effectiveness of rapid, ICU-based, syndromic PCR in hospital-acquired pneumonia: analysis of the INHALE WP3 multi-centre RCT
CONCLUSIONS: We found lower average ICU costs with the Pneumonia Panel. The pneumonia panel was cost-effective in terms of antibiotic stewardship, but not clinical cure.
-
Callback time preference for prescreening visits among Black residents in the Boston area: findings from two randomized controlled trials
CONCLUSION: Contacting participants during their preferred callback time was associated with reaching them and completing a prescreening interview. These data highlight the importance of study teams’ flexibility in outreach time to enhance the recruitment of Black adults into cardiovascular clinical trials.
-
Sleep quality patterns in patients with heart failure: a person-centred latent class analysis from a secondary analysis of the MOTIVATE-HF trial
CONCLUSIONS: Patients with HF exhibit heterogeneous sleep quality patterns with specific clinical and psychological profiles. These findings highlight the need for personalised interventions, systematic sleep assessments and the integration of cardiac rehabilitation strategies into standard HF care.