Emily C Timm April 27, 2024 Sensors (Basel). 2024 Apr 18;24(8):2586. doi: 10.3390/s24082586. ABSTRACT FXTAS is a neurodegenerative disorder occurring in some Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene premutation carriers (PMCs) and is characterized by cerebellar ataxia, tremor, and cognitive deficits that negatively impact balance and gait and increase fall risk. Dual-tasking (DT) cognitive-motor…
Tejaswini Manavi April 27, 2024 Sensors (Basel). 2024 Apr 16;24(8):2546. doi: 10.3390/s24082546. ABSTRACT Heart failure (HF) is a multi-faceted, complex clinical syndrome characterized by significant morbidity, high mortality rate, reduced quality of life, and rapidly increasing healthcare costs. A larger proportion of these costs comprise both ambulatory and emergency department visits, as well as hospital…
Faraz Sadrzadeh-Afsharazar April 27, 2024 Sensors (Basel). 2024 Apr 14;24(8):2512. doi: 10.3390/s24082512. ABSTRACT This study presents phosphenotron, a device for enhancing the sensory spatial resolution of phosphenes in the visual field (VF). The phosphenotron employs a non-invasive transcranial alternating current stimulation (NITACS) to modulate brain activity by applying weak electrical currents to the scalp or…
Eleftheria Kampouri April 27, 2024 Viruses. 2024 Mar 24;16(4):498. doi: 10.3390/v16040498. ABSTRACT HHV-6B reactivation affects approximately half of all allogeneic hematopoietic cell transplant (HCT) recipients. HHV-6B is the most frequent infectious cause of encephalitis following HCT and is associated with pleiotropic manifestations in this setting, including graft-versus-host disease, myelosuppression, pneumonitis, and CMV reactivation, although the…
Henning Zelba April 27, 2024 Vaccines (Basel). 2024 Apr 9;12(4):397. doi: 10.3390/vaccines12040397. ABSTRACT Ovarian cancer is one of the most common cancers among women and the most lethal malignancy of all gynecological cancers. Surgery is promising in the early stages; however, most patients are first diagnosed in the advanced stages, where treatment options are limited.…
Ricardo Corona-Torres April 27, 2024 Vaccines (Basel). 2024 Apr 9;12(4):395. doi: 10.3390/vaccines12040395. ABSTRACT Campylobacter is a major cause of acute gastroenteritis in humans, and infections can be followed by inflammatory neuropathies and other sequelae. Handling or consumption of poultry meat is the primary risk factor for human campylobacteriosis, and C. jejuni remains highly prevalent in…
Angelo Michele Inchingolo April 27, 2024 Pharmaceuticals (Basel). 2024 Apr 22;17(4):542. doi: 10.3390/ph17040542. ABSTRACT The goal of this review is to shed light on the management of orofacial discomfort after a cancer diagnosis in the head and neck region. A search was conducted on PubMed, Scopus, and Web of Science to identify studies on postoperative…
Ralph Brattsand April 27, 2024 Pharmaceuticals (Basel). 2024 Apr 15;17(4):503. doi: 10.3390/ph17040503. ABSTRACT The introduction of inhaled corticosteroids (ICSs) changed over a few decades the treatment focus of mild-to-moderate asthma from bronchodilation to reduction in inflammation. This was achieved by inhaling a suitable corticosteroid (CS), giving a high, protracted airway concentration at a low total…
Tiffany W Chow April 27, 2024 Pharmaceuticals (Basel). 2024 Mar 22;17(4):408. doi: 10.3390/ph17040408. ABSTRACT Brain somatic gene recombination (SGR) and the endogenous reverse transcriptases (RTs) that produce it have been implicated in the etiology of Alzheimer’s disease (AD), suggesting RT inhibitors as novel prophylactics or therapeutics. This retrospective, proof-of-concept study evaluated the incidence of AD…
Diana Trujillo-Benítez April 27, 2024 Pharmaceutics. 2024 Apr 12;16(4):532. doi: 10.3390/pharmaceutics16040532. ABSTRACT Recently, we reported a new fibroblast activation protein (FAP) inhibitor radiopharmaceutical based on the 99mTc-((R)-1-((6-hydrazinylnicotinoyl)-D-alanyl) pyrrolidin-2-yl) boronic acid (99mTc-HYNIC-D-Alanine-BoroPro)(99mTc-HYNIC-iFAP) structure for tumor microenvironment SPECT imaging. This research aimed to synthesize 68Ga-[2,2′,2″,2‴-(2-(4-(2-(5-(((S)-1-((S)-2-boronopyrrolidin-1-yl)-1-oxopropan-2-yl)carbamoyl)pyridin-2-yl)hydrazine-1-carbothioamido)benzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid] (68Ga-DOTA-D-Alanine-BoroPro)(68Ga-iFAP) as a novel radiotracer for PET imaging and evaluate its…