Category Added in a WPeMatico Campaign
Chronic Spontaneous Urticaria (CSU) significantly affects quality of life. This study evaluates the efficacy of histaglobulin combined with antihistamine (bilastine) versus antihistamine alone in CSU management. A single-center, open-label, randomized trial was conducted in the dermatology OPD of a tertiary care hospital from September 2023 to August 2024. Fifty-seven eligible participants aged > 18 years…
CONCLUSIONS: Task-oriented circuit training in conjunction with a designed physiotherapy program is more effective in improving gait kinematics, pelvic symmetry, and endurance of trunk muscles among children with hemiplegia.
OBJECTIVE: Postpartum hemorrhage (PPH) is the leading cause of maternal death. Identifying excessive bleeding is crucial, but there is no gold standard for its measurement. We aimed to assess accordance between two formulas for calculated blood loss (CBL) and weight-based blood loss (WBBL) to determine if CBL has a place in either the clinical or…
CONCLUSION: High PFKFB3 is associated with a larger reduction of IBTR after radiotherapy but PFKFB3 cannot reliably be used as a predictive marker of sensitivity to adjuvant radiotherapy in breast cancer. PFKFB3 expression differed with subtype, indicating that it may be a better marker among Luminal A and HER2 positive tumors, but this is yet…
CONCLUSIONS: The Friend chatbot offers a scalable, cost-effective solution for psychological support, particularly in crisis situations where traditional therapy may not be accessible. Although traditional therapy remains more effective in reducing anxiety, a hybrid model combining AI support with human interaction could optimize mental health care, especially in underserved areas or during emergencies. Further research…
CONCLUSIONS: The 40 mg b.i.d. and 80 mg q.d. regimens are comparable in their daily exposure, supporting the use of the two dosing regimens in newly diagnosed and previously treated CML-CP patients. The PK of asciminib is insensitive to ethnic differences and no dose adjustment is required for severe renal and hepatic impaired patients.
CONCLUSIONS: Playing music for <7 minutes is a versatile, effective, and low-risk method for anxiolysis in women awaiting elective cesarean delivery.
CONCLUSIONS: Arimoclomol had no significant effects on the qMRI measurements evaluated, consistent with clinical outcomes from the main trial. The qMRI measurements demonstrated both validity and responsiveness, further supporting their potential utility as biomarkers in IBM.
BACKGROUND: There is pressing need to develop and evaluate clinically sound approaches to supporting the engagement between patients who have inherited cancer susceptibility and their relatives who may share it. Identifying and engaging patients with an inherited cancer susceptibility in the community is a potentially powerful strategy to reduce the gap in genetic risk evaluation…
CONCLUSIONS: Peer group intervention for 6 weeks among municipal employees with chronic pain is partially effective. The number of areas of pain and pain self-efficacy were more sensitive indicators of change than the pain intensity. Any primary care unit with sufficient resources may implement the intervention.