Clinical Trials
Category Added in a WPeMatico Campaign
-
Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial
Activation of adenosine triphosphate-sensitive potassium (K ATP ) channels has been implicated in triggering migraine attacks. However, whether the opening of these channels provoke cluster headache attacks remains undetermined. The hallmark of cluster headache is a distinct cyclical pattern of recurrent, severe headache episodes, succeeded by intervals of remission where no symptoms are present. In…
-
Effectiveness of Self-Training With a Web-Based Digital Health Application Versus Physiotherapy in the Treatment of Disorders of the Patella: Randomized Controlled Trial
CONCLUSIONS: Our findings indicated that the investigated DHA is superior to SHI-PT for treating disorders of the patella. Therefore, DHA has been approved by the German Federal Institute for Drugs and Medical Devices for treating disorders of the patella in persons of all sexes aged ≥12 years.
-
Autologous mesenchymal stem cells as a component of multidisciplinary rehabilitation of war participants with severe forms of chronic critical lower limb ischemia and pain syndroms
CONCLUSION: Conclusions: The implementation of MRP, integrating MSCs therapy, led to significant improvements in pain relief, tissue regeneration and overall functional recovery in patients with CCLLI, particularly those with military-related injuries, favouring the reduction of the risk of lower limb amputation.
-
The Effect of Chewing Gum in Managing Labor Pain Intensity and Anxiety Level in Primiparous Women: A Randomized Controlled Trial
CONCLUSION: Chewing gum is a practical alternative method for decreasing anxiety and pain intensity during childbirth in primiparous women.Trial Registration Number: IRCT20100510003902N5.
-
A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial for the Efficacy and Safety of a Novel Nutraceutical for Mild-to-Moderate Acne
CONCLUSION: The oral nutraceutical significantly improves mild-to-moderate acne and overall skin health in adult women when compared to a placebo.
-
Caffeine’s influence on vertical jump height: a real-life collegiate student-athlete approach
CONCLUSIONS: A 5 mg/kg caffeine dose, compliant with NCAA thresholds, did not enhance vertical jump performance in habituated collegiate athletes, challenging prior assertions of its universal ergogenicity for ballistic tasks. While sex differences in baseline performance persisted, caffeine did not modulate these disparities, implicating neuromuscular and anthropometric factors as primary determinants. The absence of ergogenic…
-
Effectiveness of Nurse-Led Psychoeducation on Knowledge and Psychological Distress in Cancer Patients Undergoing Radiological Imaging: A Randomized Controlled Trial
CONCLUSION: Nurse-led psychoeducation effectively improved knowledge and reduced anxiety in patients with cancer undergoing radiological imaging. Integrating such interventions into pre-imaging protocols can enhance patient preparedness and reduce psychological distress. Further research should explore the long-term effects and adaptability of this intervention in diverse healthcare settings.
-
Bringing malaria diagnosis and treatment closer to the people: economic rationale for expanding malaria community case management to all ages in a rural district in Madagascar
CONCLUSIONS: Age-expanded mCCM is highly cost-effective and can enhance malaria treatment access in resource-limited settings.
-
Kinesio Taping, Wrist Splinting, and Epicondylitis Bandaging in Managing Lateral Epicondylitis: A Prospective Comparative Study
BACKGROUND We assessed the treatment outcomes of patients assigned by sequential randomization to 3 groups: epicondylitis bandaging, wrist dorsiflexion splinting, and kinesio taping. MATERIAL AND METHODS Fifty-four patients diagnosed with lateral epicondylitis were included in the study and randomly divided into 3 groups (n=18): epicondylitis bandage, wrist dorsiflexion splint, and kinesio tape. Patients were evaluated…
-
A study on the safety and efficacy of a robotic-assisted navigation and positioning system in CT-guided percutaneous biopsy of thoracic and abdominal tumors
CONCLUSION: The robotic puncture navigation system improves the success rate of localization and reduces the number of puncture adjustments and CT scans; therefore, it is superior to the traditional step-by-step puncture method.