J Drugs Dermatol. 2025 Aug 1;24(8):782-786. doi: 10.36849/JDD.9238.
ABSTRACT
BACKGROUND: Psoriasis is a common skin condition that affects the physical and emotional well-being of patients. Moisturizers have been shown to significantly improve skin condition and quality of life in this patient population. Skin afflictions such as atopic dermatitis and pruritis share etiological similarities with psoriasis, and oatmeal (Avena sativa)-containing lotion has proven effective in treating the symptoms of those conditions. However, data on the use of an over-the-counter oatmeal-containing lotion alone to treat the symptoms of psoriasis are limited.
METHODS: An open-label clinical study of 60 adult subjects with sensitive skin and mild to moderate psoriasis was completed. Subjects applied a topical lotion containing oat flour, oat oil, and oat extract with avenanthramides (the oatmeal-containing lotion) on the entire body, with a focus on dry patches, at least once daily for 4 weeks as the sole intervention to manage their symptoms. The primary objective of the study was to assess the efficacy and tolerability of the oatmeal-containing lotion in patients with psoriasis. Product satisfaction was also measured after 4 weeks of use.
RESULTS: After 4 weeks of treatment, subjects reported statistically significant improvements in all self-assessment parameters of skin condition, with no adverse effects reported. Overall, subjects expressed high satisfaction with the product.
CONCLUSIONS: This study provides evidence supporting the efficacy and tolerability of a topical, over-the-counter lotion containing oat flour, oat oil and oat extract with avenanthramides as the sole intervention for managing the symptoms of sensitive skin and mild to moderate psoriasis.
PMID:40773617 | DOI:10.36849/JDD.9238
