Altern Ther Health Med. 2025 Jul;31(4):105-109.
ABSTRACT
OBJECTIVE: This study aimed to explore the efficacy and underlying mechanism of low-temperature plasma radiofrequency ablation (LTPRFA) for the treatment of early glottic carcinoma.
METHODS: A total of 122 patients diagnosed with early glottic cancer were admitted to our hospital between February 2019 and January 2022. They were randomly assigned to either the observation group (n = 56) or the experimental group (n = 56). The observation group underwent traditional laryngeal fissure surgery, while the experimental group underwent LTPRFA. Operation-related parameters, including voice recovery, complication incidence, recurrence rate, and mucosal smoothness rate were meticulously evaluated and compared between the two groups.
RESULTS: The results revealed that the experimental group exhibited significantly better outcomes across all operation-related parameters (P < .05). Specifically, the experimental group demonstrated remarkable voice recovery compared to the observation group (P < .05). Moreover, the experimental group displayed a considerably lower incidence of complications than the observation group (P < .05). Furthermore, the experimental group exhibited a significantly higher mucosal smoothness rate compared to the observation group (P < .05), while the recurrence rate did not differ significantly between the two groups (P > .05).
CONCLUSION: Our findings demonstrate the successful application of low-temperature plasma radiofrequency ablation in the management of early glottic carcinoma. This innovative technique offers several potential advantages, including reduced intraoperative bleeding, shorter surgical duration, and hospital stay. Additionally, it promotes enhanced postoperative voice restoration and mucosal healing, while minimizing the occurrence of postoperative complications. These compelling results support the wider adoption of LTPRFA as an effective therapeutic approach for early glottic carcinoma.
PMID:40497713
