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4-hydroxy 2-methyl-N-(5-methyl-2-thiazolyl)-2H-1, 2-benzothiazin-3-carboxamide 1,1-dioxide (QP001), a novel long-lasting meloxicam formulation, may provide adequate postoperative pain relief with a good safety profile. This study aimed to evaluate the efficacy and safety of QP001 for moderate-to-severe pain following abdominal surgery. This multicenter, randomized, double-blind, placebo-controlled phase III trial recruited patients undergoing abdominal surgery at 23 centers between…
CONCLUSIONS: The visual performance of the monofocal and bifocal IOLs was as expected, with greater depth of focus but reduced contrast sensitivity for the bifocal IOL. The VirtIOL device represents a promising tool to predict the visual performance of IOLs before implantation in patients. [J Refract Surg. 2024;40(12):e911-e915.].
CONCLUSION AND DISCUSSION: Our findings suggest that Marrubium vulgare could serve as an effective and safe treatment for PCOS.
CONCLUSIONS: JZMA combined with standard treatment effectively reduced CIMT, plaque size, and serum lipid levels, thereby enhancing clinical outcomes in patients with stable angina and carotid atherosclerosis.
CONCLUSION AND DISCUSSION: Working memory treatment improved naming ability (confrontational naming, verbal fluency, and continuous speech analysis) in elderly with mild cognitive impairment. Therefore, this treatment can enhance naming skills in these individuals, making its implementation particularly important.
CONCLUSIONS: The clinical performance of bioactive injectable resin composite and nanohybrid resin composite was similar and found to be clinically acceptable after 18 months of clinical use.
CONCLUSION: Although the COCP has a slightly higher probability of being cost-effective at £20 000/QALY threshold, there remains considerable uncertainty, with only marginal differences in outcomes between the two treatments. The lower rates of further surgery and second-line medical treatment for women allocated to LAPs may make this option preferable for some women.
INTRODUCTION: With the growing older adult population, the European Union emphasizes the need to promote research in healthy aging trough multidisciplinary and innovative approaches, including the integration of advanced technologies like virtual reality (VR) in cognitive rehabilitation. This reflects the increasing awareness of the importance of addressing challenges related to neurodegenerative diseases in the older…
INTRODUCTION: The incidence of postoperative gastrointestinal dysfunction (POGD) is notably high among patients following colorectal cancer surgery, highlighting the urgency for the prompt development of efficacious preventive and therapeutic approaches. Electroacupuncture (EA) represents an intervention modality that holds promise for the management of POGD. However, the existing empirical evidence substantiating its efficacy remains scarce. The…
CONCLUSION: The changes in HbA1c were positively correlated with the dose of Coptidis Rhizoma, but not significantly with the dose of Puerariae Lobatae Radix. It demonstrated that the main drug of GQD in treating T2D patients is Coptidis Rhizoma.