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Observation on the efficacy of moxibustion with fuzi cake combined with auricular point pressing in treating anxiety and depression in newly diagnosed people living with HIV: A randomized controlled trial

Medicine (Baltimore). 2025 Sep 5;104(36):e44437. doi: 10.1097/MD.0000000000044437.

ABSTRACT

BACKGROUND: This study investigated the efficacy of moxibustion with aconite cake combined with earlobe acupressure in alleviating anxiety and depression in newly diagnosed human immunodeficiency virus patients.

METHODS: Ninety eligible patients from the Affiliated Ruikang Hospital of Guangxi University of Chinese Medicine were randomly divided into an intervention group and a control group of 45 each. The control group received conventional care, while the intervention group received the combined therapy. The treatment lasted for 3 months. Efficacy was evaluated using the self-rating anxiety scale (SAS), self-rating depression scale (SDS), and quality-of life scale before and after treatment.

RESULTS: After 3 months, the intervention group’s SAS and SDS scores were significantly lower than the control group’s (P <.05). Their quality-of-life scores and CD4 + T — lymphocyte counts improved more than the control group’s (P <.05). No significant adverse reactions occurred in the intervention group.

CONCLUSION: Moxibustion with aconite cake combined with earlobe acupressure can effectively alleviate anxiety and depression in newly diagnosed human immunodeficiency virus patients, enhance their quality-of-life, and may improve immune function. The treatment is safe and well — tolerated, with good clinical potential for application and promotion.

PMID:40922288 | DOI:10.1097/MD.0000000000044437