Zhonghua Nan Ke Xue. 2025 Feb;31(2):165-171.
ABSTRACT
OBJECTIVE: The aim of this study is to evaluate the clinical efficacy of Oxalicao Formula combined with transacupuncture in the treatment of chronic nonbacterial prostatitis （CNP）characterized by dampness-heat stasis.
METHODS: A total of 70 patients diagnosed with CNP and characterized by dampness-heat stasis were randomly divided into control group and treatment group, with 35 cases in each group. The patients in control group received Qianlie Beixi capsules． Ｗhile the patients in treatment group were administered with oxalis decoction in conjunction with acupuncture therapy which lasted for 8 weeks. Pre- and post-treatment evaluations for NIH-Chronic Prostatitis Symptom Index (NIH-CPSI), Traditional Chinese Medicine (TCM) symptom scores, urodynamic parameters, immune cell subsets and inflammatory factors were performed.
RESULTS: Ultimately, 65 patients completed the study with 33 in the treatment group and 32 in the control group. After 8 weeks of intervention, The patients in both of groups demonstrated significant improvements (P<0.05). Specifically, remarkable reductions in the NIH-CPSI total score including pain score, urination score, quality of life impact score, TCM symptom score and inflammatory cytokine levels were observed. Additionally, there were upward trend in maximum and average urinary flow rates as well as the CD4+/CD8+ ratio of immune cells(P<0.05). Compared to the control group, the treatment group exhibited superior outcomes in reducing the NIH-CPSI total score, pain score, urination score, quality of life impact score, TCM symptom score, and inflammatory cytokine levels, and increasing in CD4+/CD8+ ratios， maximum and average urine flow rates(P<0.05).
CONCLUSION: The combination of Oxalicao Formula and transacupuncture for treating CNP characterized by dampness-heat stasis demonstrates significant therapeutic benefits, which has considerable clinical application value.
PMID:40783962
