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Comparison of Postoperative Pain Using Endo-Activator Vs. Conventional Irrigation in Symptomatic Periapical Periodontitis: A Randomised Controlled Trial

J Coll Physicians Surg Pak. 2025 Jul;35(7):830-836. doi: 10.29271/jcpsp.2025.07.830.

ABSTRACT

OBJECTIVE: To compare the frequency of pain after using endo-activator and conventional irrigation in patients presenting with symptomatic periapical periodontitis following endodontic treatment by means of a visual analogue scale (VAS).

STUDY DESIGN: Randomised clinical trial. Place and Duration of the Study: Department of Operative Dentistry and Endodontics, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi, Pakistan, from September 2023 to March 2024.

METHODOLOGY: Sixty patients with symptomatic teeth requiring endodontic treatment were recruited by probability random sampling into two groups based on irrigation protocols used during endodontic treatment: Conventional needle and endo-activator irrigation system. The difference between intensity of pain in the two groups at various time intervals was assessed by Mann-Whitney U test. The postoperative pain of patients was recorded via a telephone call at 6 hours, 24 hours, and at 7th day on the visual analogue scale (VAS).

RESULTS: Pain was higher in the conventional group as compared to the endo-activator group at 6 hours, 24 hours as well as at the 7th day (p <0.001).

CONCLUSION: The intensity and severity of postoperative pain occurring in patients presenting with symptomatic periapical periodontitis was significantly reduced by the use of endo-activator when used with 2.5% NaOCl seven days after single-visit endodontic treatment.

KEY WORDS: Conventional irrigation, Endo-activator, Postoperative pain, Symptomatic periapical periodontitis, Visual analogue scale.

PMID:40605204 | DOI:10.29271/jcpsp.2025.07.830